The relevance of attention deficit hyperactivity disorder in self-limited childhood epilepsy with centrotemporal spikes

Autor(es)

Lima, Ellen Marise ^[1] ; Rzezak, Patricia ^[1] ; dos Santos, Bernardo ^[2] ; Gentil, Leticia ^[1] ; Montenegro, Maria A. ^[3] ; Guerreiro, Marilisa M. ^[3] ; Valente, Kette D. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, HCFMUSP, Hosp Clin, Dept Psychiat, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Nursing, Sao Paulo - Brazil

^[3] Univ Estadual Campinas, UNICAMP, Dept Neurol, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Epilepsy & Behavior; v. 82, p. 164-169, MAY 2018.
• Citações Web of Science: 4

Resumo

In this study, we aimed to evaluate the attentional and executive functions in patients with benign childhood epilepsy with centrotemporal spikes (BCECTS) with and without attention-deficit hyperactivity disorder (ADHD) compared with controls and compared with patients with ADHD without epilepsy. We evaluated 12 patients with BCECTS and ADHD (66.7% boys; mean age of 9.67 years); 11 children with non-ADHD BCECTS (63.6% boys; mean age of 11.91 years); 20 healthy children (75% boys; mean age of 10.15 years); and 20 subjects with ADHD without epilepsy (60% boys; mean age of 10.9 years). We used a comprehensive battery of neuropsychological tests to evaluate attentional and executive functions in their broad domains. Patients with BCECTS and ADHD had worse performance in Conners Continuous Performance Test II ( reaction time standard error {[}p = 0.008], variability {[}p = 0.033], perseverations {[}p = 0.044] and in reaction time interstimuli interval {[}p = 0.016]). Patients with ADHD showed worse performance in Trail Making Test B errors {[}p = 0.012]. In conclusion, patients with BCECTS and ADHD had worse executive and attentional performance compared with controls than non-ADHD patients with BCECTS. Regardless of the presence of epilepsy, ADHD also negatively impacted executive and attentional functions but in different executive subdomains compared with patients with epilepsy. (C) 2018 Elsevier inc. All rights reserved. (AU)

• Processo FAPESP: 15/02796-2 - Epilepsia Benigna da Infância com Paroxismos Centrotemporais - Delineamento do Perfil Executivo
• Beneficiário: Ellen Marise Lima
• Modalidade de apoio: Bolsas no Brasil - Mestrado