| Texto completo | |
| Autor(es): |
Rossi Feliciano, Marcus Antonio
[1, 2]
;
Uscategui Ramirez, Ricardo Andres
[2]
;
Maronezi, Marjury Cristina
[2]
;
Maciel, Giovanna Serpa
[2]
;
Avante, Michelle Lopes
[2]
;
Salardani Senhorello, Igor Luiz
[2]
;
Mucedola, Talita
[2]
;
Gasser, Beatriz
[2]
;
Carvalho, Cibele Figueira
[3]
;
Russiano Vicente, Wilter Ricardo
[2]
Número total de Autores: 10
|
| Afiliação do(s) autor(es): | [1] Univ Fed Reconcavo Bahia, Cruz Das Almas - Brazil
[2] UNESP Univ Estadual Paulista Julio de Mesquita Fi, Fac Ciencias Agr & Vet, Campus Jaboticabal, Jaboticabal - Brazil
[3] NAUS Nucleo Aperfeicoamento Ultrassonog Vet, Sao Paulo - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | VETERINARY RADIOLOGY & ULTRASOUND; v. 59, n. 4, p. 444-452, JUL-AUG 2018. |
| Citações Web of Science: | 2 |
| Resumo | |
Due to the importance of presurgical, noninvasive, and accurate diagnostic tools in mammary carcinoma characterization, this prospective secondary observational cohort study was designed to evaluate and compare the diagnostic accuracy of B-mode, Doppler, contrast enhancement ultrasonography, or acoustic radiation force impulse-elastography in identifying mammary carcinomas types with high degree of malignancy. A total of 246 mammary carcinomas from 141 female dogs were analyzed using B-mode, Doppler, contrast enhancement ultrasonography, and acoustic radiation force impulse ultrasonography prior to their histopathological classification according to types (simple, complex, or special) and grade (I, II, or III). Qualitative and quantitative variables were compared between carcinoma types and grades by Fisher's or analysis of variance. Diagnostic performance was estimated by receiver-operating characteristic analysis, using histopathological classification as a reference. Deformability (acoustic radiation force impulse) had a diagnostic specificity of 100% and sensitivity of 12% in identifying special carcinomas. A width:length ratio greater than 0.53 can be suggestive of special carcinoma, with 80% sensitivity and 76% specificity. Contrast wash-in and peak enhancement times lower than 7.5 and 13.5s, respectively, were indicative of complex carcinoma at 62% sensitivity and 60% specificity. Contrast wash-in, peak enhancement, and wash-out times greater than 6.5, 12.5, and 64.5s, respectively; were indicative of grade II and III carcinoma at 68% sensitivity and 62% specificity. In conclusion, B-mode ultrasonography, contrast enhancement ultrasonography, and acoustic radiation force impulse-elastography enabled the identification of some of the characteristics of high-grade mammary carcinoma types and grades in female dogs with limited accuracy. The findings from this study may contribute to oncology research and clinical management canine patients. (AU) | |
| Processo FAPESP: | 13/23901-3 - Avaliação elastográfica qualitativa e quantitativa de tumores mamários em cadelas |
| Beneficiário: | Letícia Pavan |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 12/16635-2 - Elastografia, ultrassonografia com contraste por microbolhas e Doppler como métodos de diagnóstico das neoplasias mamárias, afecções prostáticas e testiculares em cães |
| Beneficiário: | Marcus Antônio Rossi Feliciano |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |
| Processo FAPESP: | 13/06443-1 - Elastografia, ultrassonografia com contraste por microbolhas e Doppler como métodos de diagnóstico das neoplasias mamárias, afecções prostáticas e testiculares em cães |
| Beneficiário: | Marcus Antônio Rossi Feliciano |
| Modalidade de apoio: | Bolsas no Brasil - Jovens Pesquisadores |