| Full text | |
| Author(s): |
Rossi Feliciano, Marcus Antonio
[1, 2]
;
Uscategui Ramirez, Ricardo Andres
[2]
;
Maronezi, Marjury Cristina
[2]
;
Maciel, Giovanna Serpa
[2]
;
Avante, Michelle Lopes
[2]
;
Salardani Senhorello, Igor Luiz
[2]
;
Mucedola, Talita
[2]
;
Gasser, Beatriz
[2]
;
Carvalho, Cibele Figueira
[3]
;
Russiano Vicente, Wilter Ricardo
[2]
Total Authors: 10
|
| Affiliation: | [1] Univ Fed Reconcavo Bahia, Cruz Das Almas - Brazil
[2] UNESP Univ Estadual Paulista Julio de Mesquita Fi, Fac Ciencias Agr & Vet, Campus Jaboticabal, Jaboticabal - Brazil
[3] NAUS Nucleo Aperfeicoamento Ultrassonog Vet, Sao Paulo - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | VETERINARY RADIOLOGY & ULTRASOUND; v. 59, n. 4, p. 444-452, JUL-AUG 2018. |
| Web of Science Citations: | 2 |
| Abstract | |
Due to the importance of presurgical, noninvasive, and accurate diagnostic tools in mammary carcinoma characterization, this prospective secondary observational cohort study was designed to evaluate and compare the diagnostic accuracy of B-mode, Doppler, contrast enhancement ultrasonography, or acoustic radiation force impulse-elastography in identifying mammary carcinomas types with high degree of malignancy. A total of 246 mammary carcinomas from 141 female dogs were analyzed using B-mode, Doppler, contrast enhancement ultrasonography, and acoustic radiation force impulse ultrasonography prior to their histopathological classification according to types (simple, complex, or special) and grade (I, II, or III). Qualitative and quantitative variables were compared between carcinoma types and grades by Fisher's or analysis of variance. Diagnostic performance was estimated by receiver-operating characteristic analysis, using histopathological classification as a reference. Deformability (acoustic radiation force impulse) had a diagnostic specificity of 100% and sensitivity of 12% in identifying special carcinomas. A width:length ratio greater than 0.53 can be suggestive of special carcinoma, with 80% sensitivity and 76% specificity. Contrast wash-in and peak enhancement times lower than 7.5 and 13.5s, respectively, were indicative of complex carcinoma at 62% sensitivity and 60% specificity. Contrast wash-in, peak enhancement, and wash-out times greater than 6.5, 12.5, and 64.5s, respectively; were indicative of grade II and III carcinoma at 68% sensitivity and 62% specificity. In conclusion, B-mode ultrasonography, contrast enhancement ultrasonography, and acoustic radiation force impulse-elastography enabled the identification of some of the characteristics of high-grade mammary carcinoma types and grades in female dogs with limited accuracy. The findings from this study may contribute to oncology research and clinical management canine patients. (AU) | |
| FAPESP's process: | 13/23901-3 - Qualitative and quantitative elastography evaluation of mammary tumors in bitches |
| Grantee: | Letícia Pavan |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |
| FAPESP's process: | 12/16635-2 - Elastography, contrast enhanced ultrasonography and Doppler as diagnostic of method of the mammary neoplasm, prostatic and testicular diseases in canines |
| Grantee: | Marcus Antônio Rossi Feliciano |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 13/06443-1 - Elastography, contrast enhanced ultrasonography and Doppler as diagnostic of method of the mammary neoplasm, prostatic and testicular diseases in canines |
| Grantee: | Marcus Antônio Rossi Feliciano |
| Support Opportunities: | Scholarships in Brazil - Young Researchers |