Influence of Intradialytic Aerobic Training in Cerebral Blood Flow and Cognitive Function in Patients with Chronic Kidney Disease: A Pilot Randomized Controlled Trial

Autor(es):Mostrar menos -

Belik, Fernanda Stringuetta ^[1] ; Oliveira e Silva, Viviana Rugolo ^[1] ; Braga, Gabriel Pereira ^[1] ; Bazan, Rodrigo ^[1] ; Vogt, Barbara Perez ^[1] ; Teixeira Caramori, Jacqueline Costa ^[1] ; Barretti, Pasqual ^[1] ; Goncalves, Renato de Souza ^[1] ; Fortes Villas Boas, Paulo Jose ^[1] ; Hueb, Joao Carlos ^[1] ; Martin, Luis Cuadrado ^[1] ; da Silva Franco, Roberto Jorge ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ, UNESP, Div Nephrol, Dept Internal Med, Botucatu Med Sch, BR-18618687 Botucatu, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: NEPHRON; v. 140, n. 1, p. 9-17, 2018.
• Citações Web of Science: 3

Resumo

Background and Objectives: Changes in cerebral blood flow may play an important role in cognitive impairment among hemodialysis (HD) patients. Physical activity has a promising role in delaying cognitive impairment in general population, but there are only a few studies in HD to confirm this finding. We aimed to evaluate the effects of intradialytic aerobic training on cerebral blood flow and cognitive impairment in HD. Design, Setting, Participants, and Measurements: This is a pilot, controlled, randomized trial. Fifteen patients underwent intradialytic aerobic training 3 times a week for 4 months. The control group was comprised of another 15 patients. Results: Trained patients had a statistically significant improvement of cognitive impairment and basilar maximum blood flow velocity. The proportion of arteries with increased flow velocity was statistically significant between groups. Conclusions: Intradialytic aerobic training improves cognitive impairment and cerebral blood flow of patients in HD, suggesting a possible mechanism improving cognitive impairment by physical training in HD. These data still need to be confirmed by major trials. (C) 2018 S. Karger AG, Basel (AU)

• Processo FAPESP: 11/20652-7 - Influência do treinamento aeróbico intradialítico no fluxo sanguíneo cerebral e o reflexo sobre a função cognitiva e qualidade de vida em pacientes renais crônicos
• Beneficiário: Fernanda Stringuetta Belik
• Linha de fomento: Bolsas no Brasil - Doutorado