Incidence and mortality risk for respiratory tract cancer in the city of Sao Paulo, Brazil: Bayesian analysis of the association with traffic density

Autor(es)

Ribeiro, Adeylson G. ^[1] ; Baquero, Oswaldo S. ^[2] ; de Freitas, Clarice U. ^[3] ; Chiaravalotti Neto, Francisco ^[4] ; Cardoso, Maria Regina A. ^[4] ; Latorre, Maria do Rosario D. O. ^[4] ; Nardocci, Adelaide C. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Publ Hlth, Dept Environm Hlth, Av Dr Arnaldo 715, BR-01246904 Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Sch Vet Med, Dept Prevent Vet Med & Anim Hlth, Av Prof Dr Orlando M de Paiva 87, BR-05508270 Sao Paulo, SP - Brazil

^[3] State Dept Hlth, Ctr Epidemiol Surveillance, Av Dr Arnaldo 351, BR-01246000 Sao Paulo, SP - Brazil

^[4] Univ Sao Paulo, Sch Publ Hlth, Dept Epidemiol, Av Dr Arnaldo 715, BR-01246904 Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: CANCER EPIDEMIOLOGY; v. 56, p. 53-59, OCT 2018.
• Citações Web of Science: 1

Resumo

Background: There is evidence that exposure to traffic-related air pollution is related to the incidence of and mortality associated with lung cancer. The aim of this study was to perform a spatial analysis, with a Bayesian approach, to test the hypothesis that high traffic density is associated with increased respiratory tract cancer incidence and mortality risk among individuals over 20 years of age residing in the city of Sao Paulo, Brazil. Methods: We employed data from two different databases: the Sao Paulo Municipal Population-Based Cancer Registry (2002-2011 cancer incidence data); and the Mortality Database of the Sao Paulo Municipal Health Department (2002-2013 cancer mortality data). The relationships between the number of cases of respiratory tract cancer in each area analyzed and the standardized covariates-traffic density and the Municipal Human Development Index (MHDI)-were evaluated with a Besag-York-Mollie ecological model with relative risks (RRs) estimates. Results: Per 1-unit standard-deviation increase in traffic density and in the MHDI, the RR for respiratory tract cancer incidence was 1.07 (95% CI: 1.02-1.13) and 1.25 (95% CI: 1.18-1.32), respectively, whereas the RR for mortality was 1.04 (95% CI: 0.99-1.09) and 1.23 (95% CI: 1.16-1.30), respectively. Conclusion: Our findings support the hypothesis that residing in areas with high traffic density is associated with increased respiratory tract cancer incidence and mortality risk in the city of Sao Paulo. (AU)

• Processo FAPESP: 06/61616-5 - Estudo da relação entre doenças respiratórias e cardiovasculares e poluição veicular nas regiões metropolitanas do estado de São Paulo com a finalidade de subsidiar a estruturação das atividades do programa de vigilância em saúde e qualidade do ar
• Beneficiário: Maria Regina Alves Cardoso
• Modalidade de apoio: Auxílio à Pesquisa - Pesquisa em Políticas Públicas para o SUS