| Texto completo | |
| Autor(es): Mostrar menos - |
Rath, Susanne
[1]
;
Fostier, Anne Helene
[1]
;
Pereira, Leandro Alves
[1]
;
Dioniso, Andreza Camilotti
[1]
;
Ferreira, Fabricio de Oliveira
[1]
;
Doretto, Keity Margareth
[1]
;
Peruchi, Livia Maniero
[1]
;
Viera, Alessandra
[1]
;
de Oliveira Neto, Odilon Franca
[1]
;
Dal Bosco, Sandra Maria
[1]
;
Martinez-Mejia, Monica J.
[1]
Número total de Autores: 11
|
| Afiliação do(s) autor(es): | [1] Univ Estadual Campinas, Dept Analyt Chem, Inst Chem, POB 6154, BR-13084971 Campinas, SP - Brazil
Número total de Afiliações: 1
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Chemosphere; v. 214, p. 111-122, JAN 2019. |
| Citações Web of Science: | 7 |
| Resumo | |
Brazil is one of the world's largest producers of animal protein, requiring the large-scale use of veterinary drugs. The administration of antimicrobials and antiparasitics is a common practice. However, there is a lack of information on how these drugs impact the environment. Antimicrobials are capable of altering the soil microbial population and are responsible for the development of multidrug-resistant microbial strains. Therefore, it is important to evaluate the fate and transport of these compounds in the environment, and one parameter used for this purpose is the soil-water partition coefficient. In this work, an assessment was made of the soil sorption behaviors of 18 drugs from seven different families, including antimicrobials (sulfonamides, fluoroquinolones, amphenicols, and macrolides) and antiparasitic drugs (milbemycin, avermectins, and benzimidazoles). Seven subtropical soils of different textural classes were tested. The Freundlich sorption coefficients, expressed as mu g(1-1/n) (cm(3))(1/n) g(-1), were in the following ranges: 0.45 to 19 (sulfonamides), 72 to 2410 (fluoroquinolones), 9 to 58 (thiabendazole), 0.03 to 0.48 (florfenicol), 105 to 424 (moxidectin), 14 to 184 (avermectins), and 1.5 to 74 (macrolides). The results showed that the drugs belonging to the same family, with chemical structures in common, presented similar behaviors regarding sorption and desorption, for the different soils tested and are generally in agreement with soils from temperate regions. The data set obtained in this work give an overview of the fate of the veterinary drugs in Brazilian subtropical soils with different textures and composition and can be very helpful for exposure risk assessments. (C) 2018 Elsevier Ltd. All rights reserved. (AU) | |
| Processo FAPESP: | 12/01767-0 - Sorção e degradação de fármacos de uso veterinário em solos |
| Beneficiário: | Susanne Rath |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 14/16995-4 - Dinâmica de antimicrobianos macrolídeos em solos |
| Beneficiário: | Sandra Maria Dal Bosco |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 13/25670-9 - Antiparasitários em solos brasileiros: estudo de sorção, dessorção e degradação |
| Beneficiário: | Fabricio de Oliveira Ferreira |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 13/09543-7 - Resíduos de medicamentos veterinários no ambiente |
| Beneficiário: | Susanne Rath |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 18/03571-2 - Fármacos no Ecossistema Aquático |
| Beneficiário: | Susanne Rath |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |