| Full text | |
| Author(s): Show less - |
Rath, Susanne
[1]
;
Fostier, Anne Helene
[1]
;
Pereira, Leandro Alves
[1]
;
Dioniso, Andreza Camilotti
[1]
;
Ferreira, Fabricio de Oliveira
[1]
;
Doretto, Keity Margareth
[1]
;
Peruchi, Livia Maniero
[1]
;
Viera, Alessandra
[1]
;
de Oliveira Neto, Odilon Franca
[1]
;
Dal Bosco, Sandra Maria
[1]
;
Martinez-Mejia, Monica J.
[1]
Total Authors: 11
|
| Affiliation: | [1] Univ Estadual Campinas, Dept Analyt Chem, Inst Chem, POB 6154, BR-13084971 Campinas, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | Chemosphere; v. 214, p. 111-122, JAN 2019. |
| Web of Science Citations: | 7 |
| Abstract | |
Brazil is one of the world's largest producers of animal protein, requiring the large-scale use of veterinary drugs. The administration of antimicrobials and antiparasitics is a common practice. However, there is a lack of information on how these drugs impact the environment. Antimicrobials are capable of altering the soil microbial population and are responsible for the development of multidrug-resistant microbial strains. Therefore, it is important to evaluate the fate and transport of these compounds in the environment, and one parameter used for this purpose is the soil-water partition coefficient. In this work, an assessment was made of the soil sorption behaviors of 18 drugs from seven different families, including antimicrobials (sulfonamides, fluoroquinolones, amphenicols, and macrolides) and antiparasitic drugs (milbemycin, avermectins, and benzimidazoles). Seven subtropical soils of different textural classes were tested. The Freundlich sorption coefficients, expressed as mu g(1-1/n) (cm(3))(1/n) g(-1), were in the following ranges: 0.45 to 19 (sulfonamides), 72 to 2410 (fluoroquinolones), 9 to 58 (thiabendazole), 0.03 to 0.48 (florfenicol), 105 to 424 (moxidectin), 14 to 184 (avermectins), and 1.5 to 74 (macrolides). The results showed that the drugs belonging to the same family, with chemical structures in common, presented similar behaviors regarding sorption and desorption, for the different soils tested and are generally in agreement with soils from temperate regions. The data set obtained in this work give an overview of the fate of the veterinary drugs in Brazilian subtropical soils with different textures and composition and can be very helpful for exposure risk assessments. (C) 2018 Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 12/01767-0 - Sorption and degradation of veterinary drugs in soil |
| Grantee: | Susanne Rath |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 14/16995-4 - Dynamics of macrolide antimicrobials in soils |
| Grantee: | Sandra Maria Dal Bosco |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 13/25670-9 - Antiparasitic in Brazilian soils: study of sorption, desorption and degradation |
| Grantee: | Fabricio de Oliveira Ferreira |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 13/09543-7 - Residues of veterinary drugs in the environment |
| Grantee: | Susanne Rath |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 18/03571-2 - Pharmaceuticals in the Aquatic Environment. |
| Grantee: | Susanne Rath |
| Support Opportunities: | Regular Research Grants |