Predictors of depression and anxiety during adolescence: the impact of birth weight

Autor(es)

Costa Machado, Fernanda ^[1] ; Souza Vitalle, Maria S. ^[2] ; Franco, Maria ^[3]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Div Translat Med, Sch Med, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Pediat, Sch Med, Sao Paulo - Brazil

^[3] Univ Fed Sao Paulo, Sch Med, Div Nephrol, Rua Botucatu 703, BR-04023062 Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: MINERVA PEDIATRICA; v. 70, n. 5, p. 430-437, OCT 2018.
• Citações Web of Science: 0

Resumo

BACKGROUND: A complex association has been observed between birth weight (BW) and depression/anxiety symptoms at various stages of life. The purpose of this study was to evaluate whether adolescents with low or insufficient BW were more likely to report depressive/anxiety symptoms. METHODS: A cross-sectional study was conducted with 102 adolescents (40 boys and 62 girls). RESULTS: Our results demonstrated that the incidence of depressive symptoms was 63% in the first BW quartile and 20% in the fourth quartile. Similarly, we observed that anxiety symptoms were present in 83% of the adolescents in the first BW quartile, followed by 36% in the fourth BW quartile. After adjustment, our study identified potential risk factors that were associated with anxiety symptoms, including female gender (P=0.026) and having a BW in the first quartile (P=0.049). Moreover, the adjusted odds of having depression were 4.5 times higher in adolescents with BW in the lowest quartile (P=0.035). We also found that the incidence of depressive symptoms among females was 61% in the first BW quartile and 30% in the fourth BW quartile and that it was 67% versus 12%, respectively, among males. Finally, a model that used anxiety symptoms as the dependent variable produced similar data. CONCLUSIONS: Our findings suggest that a deleterious fetal environment appears to have a significant impact on psychiatric issues. (AU)

• Processo FAPESP: 13/03139-0 - Inter-relação do peso ao nascer, treinamento físico e níveis pressóricos: uma abordagem clínica e experimental sobre o papel das células progenitoras endoteliais
• Beneficiário: Maria Do Carmo Pinho Franco
• Modalidade de apoio: Auxílio à Pesquisa - Regular