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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Predictors of depression and anxiety during adolescence: the impact of birth weight

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Author(s):
Costa Machado, Fernanda [1] ; Souza Vitalle, Maria S. [2] ; Franco, Maria [3]
Total Authors: 3
Affiliation:
[1] Univ Fed Sao Paulo, Div Translat Med, Sch Med, Sao Paulo - Brazil
[2] Univ Fed Sao Paulo, Dept Pediat, Sch Med, Sao Paulo - Brazil
[3] Univ Fed Sao Paulo, Sch Med, Div Nephrol, Rua Botucatu 703, BR-04023062 Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: MINERVA PEDIATRICA; v. 70, n. 5, p. 430-437, OCT 2018.
Web of Science Citations: 0
Abstract

BACKGROUND: A complex association has been observed between birth weight (BW) and depression/anxiety symptoms at various stages of life. The purpose of this study was to evaluate whether adolescents with low or insufficient BW were more likely to report depressive/anxiety symptoms. METHODS: A cross-sectional study was conducted with 102 adolescents (40 boys and 62 girls). RESULTS: Our results demonstrated that the incidence of depressive symptoms was 63% in the first BW quartile and 20% in the fourth quartile. Similarly, we observed that anxiety symptoms were present in 83% of the adolescents in the first BW quartile, followed by 36% in the fourth BW quartile. After adjustment, our study identified potential risk factors that were associated with anxiety symptoms, including female gender (P=0.026) and having a BW in the first quartile (P=0.049). Moreover, the adjusted odds of having depression were 4.5 times higher in adolescents with BW in the lowest quartile (P=0.035). We also found that the incidence of depressive symptoms among females was 61% in the first BW quartile and 30% in the fourth BW quartile and that it was 67% versus 12%, respectively, among males. Finally, a model that used anxiety symptoms as the dependent variable produced similar data. CONCLUSIONS: Our findings suggest that a deleterious fetal environment appears to have a significant impact on psychiatric issues. (AU)

FAPESP's process: 13/03139-0 - The interrelationship of birth weight, physical training and blood pressure levels: a clinical and experimental approach on the role of endothelial progenitor cells
Grantee:Maria Do Carmo Pinho Franco
Support Opportunities: Regular Research Grants