Dataset for the role of sustained attention in memory formation of transgenic mice for Alzheimer's disease

Autor(es)

Schowe, Natalia Mendes ^[1] ; de Oliveira, Eduardo Moreira ^[2] ; Buck, Hudson Sousa ^[3] ; Viel, Tania Araujo ^{[4, 1]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Biomed Sci, Grad Course Pharmacol, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Med, Dept Cognit Neurol, Grad Course Neurol, Sao Paulo - Brazil

^[3] Santa Casa Sao Paulo Sch Med Sci, Dept Physiol Sci, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Sch Arts Sci & Humanities, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: DATA IN BRIEF; v. 6, p. 763-768, MAR 2016.
• Citações Web of Science: 0

Resumo

Weekly submission of rats to active avoidance apparatus can be considered a neurostimulation strategy, once it can improve memory and can increase the density of receptors from different neurotransmitter systems in brain areas related to memory. These benefits were observed in rats chronically infused with amyloid-beta peptide. In the present work it is presented that the same benefit for memory was observed in five months old transgenic mice for Alzheimers disease (TG-PDGFB-APP(Sw,Ind)). However, at this age, no change in density of nicotinic receptors was observed. (C) 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CCBY license. (AU)

• Processo FAPESP: 07/07433-9 - Estudo da neuroplasticidade colinérgica nicotínica na amígdala, após estimulação cognitiva, em um modelo animal de neurodegeneração e no envelhecimento
• Beneficiário: Tânia Araújo Viel
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 09/15973-9 - Influência da estimulação cognitiva sobre o sistema colinérgico central de camundongos transgênicos para doença de Alzheimer
• Beneficiário: Natália Mendes Schowe
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica