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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Predictors of vitamin A status among pregnant women in western Brazilian Amazon

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Autor(es):
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Neves, Paulo A. R. [1] ; Campos, Chiara A. S. [1] ; Malta, Maira B. [1] ; Lourenco, Barbara H. [1] ; Castro, Marcia C. [2] ; Cardoso, Marly A. [1] ; Manitto, Alicia Matijasevich [3] ; Lourenco, Barbara Hatzlhoffer [3] ; Malta, Maira Barreto [3] ; Cardoso, Marly Augusto [3] ; Ribeiro Neves, Paulo Augusto [3] ; Agostinho Gimeno, Suely Godoy [4] ; da Silva, Bruno Pereira [5] ; de Souza, Rodrigo Medeiros [5] ; de Castro, Marcia Caldas [6] ; Grp, MINA Brazil Study
Número total de Autores: 16
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, Ave Doutor Arnaldo 715, BR-01246904 Sao Paulo, SP - Brazil
[2] Harvard TH Chan Sch Publ Hlth, Dept Global Hlth & Populat, 677 Huntington Ave, Boston, MA 02115 - USA
[3] Univ Sao Paulo, Sao Paulo - Brazil
[4] Univ Fed Sao Paulo, Sao Paulo, SP - Brazil
[5] Univ Fed Acre, Cruzeiro Do Sul - Brazil
[6] Harvard TH Chan Sch Publ Hlth, Boston, MA - USA
Número total de Afiliações: 6
Tipo de documento: Artigo Científico
Fonte: BRITISH JOURNAL OF NUTRITION; v. 121, n. 2, p. 202-211, JAN 28 2019.
Citações Web of Science: 0
Resumo

Determining the predictors of serum retinol at mid-pregnancy is relevant for planning interventions aimed at improving vitamin A status of pregnant women and their offspring. This prospective study assessed predictors of serum retinol at the beginning of the third trimester of pregnancy. We enrolled 442 pregnant women living in the urban area of Cruzeiro do Sul, Western Brazilian Amazon. Demographic, socioeconomic, environmental and clinical characteristics as well as obstetric history, anthropometric, dietary and biochemical data, including serum retinol, were gathered between 16 and 20 gestational weeks. Serum retinol also measured at the beginning of the third trimester of pregnancy (approximately 28 gestational weeks) was the outcome of interest. Multiple linear regression models were used to evaluate associations with the outcome. Overall, the following variables explained serum retinol at the beginning of the third trimester of pregnancy in the adjusted model (R-2 = 114 %): seasonality (winter season - November to April; beta= 0.134; 95% CI 0-063, 0.206), weekly consumption of Amazonian fruits (beta = 0.087; 95% CI 0.012, 0.162) and retinol concentrations between 16 and 20 gestational weeks (beta= 0.045; 95% CI 0.016, 0.074) were positively associated, whereas having a smoker in the house was negatively associated (beta=-0.087; 95% CI: -0.166, -0.009). Consumption of pro-vitamin A-rich fruits by pregnant women should be encouraged. Passive smoking may play a role in decreasing vitamin A status as a proxy of smoking exposure during pregnancy. (AU)

Processo FAPESP: 16/00270-6 - Estudo MINA - Materno-Infantil no Acre: coorte de nascimentos da Amazônia Ocidental Brasileira
Beneficiário:Marly Augusto Cardoso
Modalidade de apoio: Auxílio à Pesquisa - Temático