Impact of combining acerola by-product with a probiotic strain on a gut microbiome model

Autor(es)

Bianchi, Fernanda ^[1] ; Lopes, Natalia Pontin ^[1] ; Tallarico Adorno, Maria Angela ^[2] ; Sakamoto, Isabel Kimiko ^[2] ; Genovese, Maria Ines ^[3] ; Isay Saad, Susana Marta ^{[4, 5]} ; Sivieri, Katia ^[1]

Afiliação do(s) autor(es)

^[1] State Univ Sao Paulo UNESP, Sch Pharmaceut Sci, Dept Food & Nutr, Rodovia Araraquara Jau Km 1 S-N, BR-14801902 Araraquara, SP - Brazil

^[2] Univ Sao Paulo, Sch Engn Sao Carlos, Dept Hydraul & Sanitat, Sao Carlos, SP - Brazil

^[3] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Food & Expt Nutr, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Dept Biochem & Pharmaceut Technol, Sao Paulo - Brazil

^[5] Univ Sao Paulo, Food Res Ctr, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION; v. 70, n. 2, p. 182-194, FEB 17 2019.
• Citações Web of Science: 1

Resumo

In this study, we first investigated the survival of three probiotic strains, individually and combined with acerola by-product during simulated gastrointestinal conditions. Next, we investigated the effects of acerola by-product combined with Bifidobacterium longum BB-46 on a gut microbiota model (SHIME (R)). Chemical composition, total phenolic compounds, antioxidant activity of the acerola by-product and microbial counts, denaturing gradient gel electrophoresis (DGGE), ammonium ions () and short-chain fatty acids (SCFAs) analysis of the SHIME (R) samples were performed. Acerola by-product revealed high protein and fibre, reduced lipid contents, and showed to be an excellent source of total phenolic compounds with high in vitro antioxidant activity. A decreased amount of in the ascending colon and an increase (p < .05) in SCFAs were observed in the three regions of colon during treatment with BB-46 and acerola by-product. BB-46 combined with acerola by-product showed positive effects on the gut microbiota metabolism in SHIME (R) model. (AU)

• Processo FAPESP: 15/08228-6 - Seleção e avaliação da combinação entre resíduos de frutas tropicais e cepas probióticas na modulação da microbiota intestinal de indivíduos obesos em relação à de eutróficos utilizando simulador do ecossistema microbiano humano.
• Beneficiário: Fernanda Bianchi
• Linha de fomento: Bolsas no Brasil - Doutorado
• Processo FAPESP: 15/13965-0 - Seleção e avaliação da combinação entre resíduos de frutas tropicais e cepas probióticas na modulação da microbiota intestinal de indivíduos obesos em relação à de eutróficos utilizando simulador do ecossistema microbiano humano
• Beneficiário: Katia Sivieri
• Linha de fomento: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/50506-8 - Bioactive components from by-products of food processing used in a symbiotic approach for improving human health and well-being (BioSyn)
• Beneficiário: Susana Marta Isay Saad
• Linha de fomento: Auxílio à Pesquisa - Temático