Sclerosing Polycystic Adenosis of Tongue

Autor(es)

Braz-Silva, Paulo Henrique ^{[1, 2]} ; do Canto, Alan Motta ^[3] ; Oliveira, Leticia ^[1] ; Martins, Fabiana ^[4] ; Pereira da Costa, Alessandro Antonio ^[5] ; Costa Hanemann, Joao Adolfo ^[6]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Div Gen Pathol, Dept Stomatol, Sch Dent, Av Prof Lineu Prestes 2227, BR-05508000 Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Lab Virol, Inst Trop Med Sao Paulo, Sao Paulo, SP - Brazil

^[3] Santa Casa Sao Paulo Sch Med Sci, Unit Oral & Maxillofacial Surg, Sao Paulo, SP - Brazil

^[4] Univ Santo Amaro, Dept Dent, Sao Paulo, SP - Brazil

^[5] Univ Fed Alfenas, Dept Pathol & Parasitol, Inst Biomed Sci, Alfenas, MG - Brazil

^[6] Univ Fed Alfenas, Sch Dent, Alfenas, MG - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BULLETIN OF TOKYO DENTAL COLLEGE; v. 59, n. 2, p. 121-125, 2018.
• Citações Web of Science: 1

Resumo

Sclerosing polycystic adenosis (SPA) is a rare benign lesion of the salivary glands which appears histologically similar to sclerosing adenosis and fibrocystic disease of the mammary gland. To date, 67 cases of SPA have been reported in the literature, with the lesion arising in the minor salivary glands in only 9. The present report describes the 10th case of SPA. The patient was a 39-year-old Brazilian man who presented with an asymptomatic nodule on the ventral surface of the tongue. Based on a clinical diagnosis of benign salivary gland neoplasm, an excisional biopsy of the lesion was performed. Histopathological examination showed lobular proliferation of ductal and acinar elements surrounded by a fibrosclerotic stroma. Many of the ductal structures exhibited cystic dilatation and were surrounded by periductal fibrosis, which is consistent with SPA findings. No recurrence of the disease was observed after a 5-year follow-up. A literature review is also discussed, focusing on both the etiology of SPA and the treatment options available. (AU)

• Processo FAPESP: 15/07727-9 - Avaliação do ambiente imunoregulatório de lesões potencialmente malignas de boca, carcinomas de boca e orofaringe relacionados ou não ao HPV.
• Beneficiário: Paulo Henrique Braz da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Regular