Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Sclerosing Polycystic Adenosis of Tongue

Full text
Author(s):
Braz-Silva, Paulo Henrique [1, 2] ; do Canto, Alan Motta [3] ; Oliveira, Leticia [1] ; Martins, Fabiana [4] ; Pereira da Costa, Alessandro Antonio [5] ; Costa Hanemann, Joao Adolfo [6]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Div Gen Pathol, Dept Stomatol, Sch Dent, Av Prof Lineu Prestes 2227, BR-05508000 Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Lab Virol, Inst Trop Med Sao Paulo, Sao Paulo, SP - Brazil
[3] Santa Casa Sao Paulo Sch Med Sci, Unit Oral & Maxillofacial Surg, Sao Paulo, SP - Brazil
[4] Univ Santo Amaro, Dept Dent, Sao Paulo, SP - Brazil
[5] Univ Fed Alfenas, Dept Pathol & Parasitol, Inst Biomed Sci, Alfenas, MG - Brazil
[6] Univ Fed Alfenas, Sch Dent, Alfenas, MG - Brazil
Total Affiliations: 6
Document type: Journal article
Source: BULLETIN OF TOKYO DENTAL COLLEGE; v. 59, n. 2, p. 121-125, 2018.
Web of Science Citations: 1
Abstract

Sclerosing polycystic adenosis (SPA) is a rare benign lesion of the salivary glands which appears histologically similar to sclerosing adenosis and fibrocystic disease of the mammary gland. To date, 67 cases of SPA have been reported in the literature, with the lesion arising in the minor salivary glands in only 9. The present report describes the 10th case of SPA. The patient was a 39-year-old Brazilian man who presented with an asymptomatic nodule on the ventral surface of the tongue. Based on a clinical diagnosis of benign salivary gland neoplasm, an excisional biopsy of the lesion was performed. Histopathological examination showed lobular proliferation of ductal and acinar elements surrounded by a fibrosclerotic stroma. Many of the ductal structures exhibited cystic dilatation and were surrounded by periductal fibrosis, which is consistent with SPA findings. No recurrence of the disease was observed after a 5-year follow-up. A literature review is also discussed, focusing on both the etiology of SPA and the treatment options available. (AU)

FAPESP's process: 15/07727-9 - Evaluation of immunoregulatory microenvironment of oral premalignant lesions, squamous cell carcinomas and oropharyngeal carcinomas related to HPV or not.
Grantee:Paulo Henrique Braz da Silva
Support Opportunities: Regular Research Grants