Cryostorage and retransplantation of ovarian tissue as an infertility treatment

Autor(es)

Amorim, Christiani A. ^[1] ; Rivas Leonel, Ellen Cristina ^{[1, 2]} ; Afifi, Yousri ^[3] ; Coomarasamy, Arri ^{[4, 5]} ; Fishel, Simon ^[6]

Afiliação do(s) autor(es)

^[1] Catholic Univ Louvain, Pole Rech Gynecol, Inst Rech Expt & Clin, Ave Mourner 52, Bte B1-52-02, B-1200 Brussels - Belgium

^[2] Sao Paulo State Univ, Inst Biosci Humanities & Exact Sci, Dept Biol, Rua Cristovao Colombo, 2265 Jardim Nazareth, BR-15054000 Sao Paulo - Brazil

^[3] Birmingham Womens NHS Fdn Trust, Dept Obstet & Gynaecol, Birmingham, W Midlands - England

^[4] Univ Birmingham, Inst Metab & Syst Res, Tommys Natl Ctr Miscarriage Res, Birmingham B15 2TT, W Midlands - England

^[5] Birmingham Womens & Childrens NHS Fdn Trust, Mindelsohn Way, Birmingham B15 2TG, W Midlands - England

^[6] CARE Fertil Grp, John Webster House, 6 Lawrence Dr, Nottingham NG8 6PZ - England

• Tipo de documento: Artigo Científico
• Fonte: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM; v. 33, n. 1, p. 89-102, FEB 2019.
• Citações Web of Science: 1

Resumo

While still considered an experimental procedure in most countries, ovarian tissue cryopreservation and transplantation has been increasingly applied worldwide to restore fertility in patients with malignant and non-malignant pathologies with risk of premature ovarian insufficiency. It has yielded more than 130 live births up to now and almost all transplanted patients recovered their ovarian function. This study summarizes ovarian tissue cryopreservation and transplantation indications, procedures, their efficacy and main results and proposes different strategies to improve this strategy. Although the main focus of this study is on ovarian tissue cryopreservation and transplantation as a strategy to restore fertility, we believe that it is also important to discuss other applications for this approach. (C) 2018 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 16/22947-8 - Técnicas para avaliação da morfologia e viabilidade de tecido reprodutivo feminino como ferramentas para auxiliar na pesquisa do câncer
• Beneficiário: Ellen Cristina Rivas Leonel
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado