A relapsing fever Borrelia and spotted fever Rickettsia in ticks from an Andean valley, central Chile

Autor(es)

Munoz-Leal, Sebastian ^[1] ; Marcili, Arlei ^{[1, 2]} ; Fuentes-Castillo, Danny ^[3] ; Ayala, Mauricio ^[4] ; Labruna, Marcelo B. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dept Med Vet Prevent & Saude Anim, Fac Med Vet & Zootecnia, Sao Paulo - Brazil

^[2] Univ Santo Amaro, Med & Bem Estar Anim, Sao Paulo - Brazil

^[3] Univ Sao Paulo, Dept Patol Expt & Comparada, Fac Med Vet & Zootecnia, Sao Paulo - Brazil

^[4] Villa Parque Bicentenario, Talca - Chile

• Tipo de documento: Artigo Científico
• Fonte: Experimental and Applied Acarology; v. 78, n. 3, p. 403-420, JUL 2019.
• Citações Web of Science: 0

Resumo

In humans, emerging infectious diseases are mostly zoonoses with ticks playing an important role as vectors. Tick-borne relapsing fever Borrelia and spotted fever Rickettsia occur in endemic foci along tropical and subtropical regions of the globe. However, both are widely neglected etiologic agents. In this study, we performed molecular analyses in order to assess the presence of Borrelia and Rickettsia DNA in ticks infesting small-mammals within a National Reserve located in the Andes Mountains, central Chile. While hard ticks were negative for the presence of both agents, sequences of four rickettsial (gltA, htrA, ompA, ompB) and two borrelial (16S rRNA and flaB) genes were obtained from larvae of an Ornithodoros sp. morphologically related with Ornithodoros atacamensis. Phylogenetic analyses indicated that the detected Borrelia and Rickettsia spp. belong to the relapsing fever and spotted fever groups, respectively. Moreover, the agents formed monophyletic clades with Rickettsia amblyommatis and `` Candidatus Borrelia johnsonii.{''}As positive ticks parasitize rodents within a highly visited National Reserve where outdoor activities are of common practice, the risk for human parasitism should not be discarded. (AU)

• Processo FAPESP: 18/02521-1 - Pesquisa de espiroquetas do grupo da febre recorrente (Spirochaetaceae: Borrelia) em carrapatos do gênero Ornithodoros (Acari: Argasidae) parasitas de humanos no Brasil
• Beneficiário: Sebastián Alejandro Munoz Leal
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado