| Texto completo | |
| Autor(es): |
Fonseca, G. W. P. D.
[1]
;
dos Santos, Marcelo Rodrigues
[1]
;
de Souza, Francis Ribeiro
[1]
;
Takayama, Liliam
[2]
;
Rodrigues Pereira, Rosa Maria
[2]
;
Negrao, Carlos Eduardo
[3, 1]
;
Nunes Alves, Maria-Janieire de Nazare
[1]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Med Sch, Heart Inst InCor, Av Dr Eneas de Carvalho Aguiar, 44 Cerqueira Cesar, BR-05403904 Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Med Sch, Rheumatol Div, Bone Metab Lab, Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, SP - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ESC HEART FAILURE; v. 7, n. 1 DEC 2019. |
| Citações Web of Science: | 0 |
| Resumo | |
Aims The definition of sarcopenia based on appendicular lean mass/height ((2)) (ALM/height ((2))) is often used, although it can underestimate the prevalence of sarcopenia in overweight/obese patients with heart failure. Therefore, new methods have been proposed to overcome this limitation. We aimed to evaluate the prevalence of sarcopenia by three methods and compare body composition in this population. Methods and results We enrolled 168 male patients with heart failure (left ventricular ejection fraction <40%). Sixty-six patients (39.3%) were identified with sarcopenia by at least one method. The lower 20th percentile defined as the cut-off point for sarcopenia was 7.03 kg/m(2), -2.32 and 0.76 for Baumgartner's (20.8%), Newman's (21.4%), and Studenski's methods (21.4%), respectively. Patients with body mass index (BMI) <25 kg/m(2) were more likely to be identified by Baumgartner's than Studenski's method (P < 0.001). However, in patients with BMI >= 25 kg/m(2), Studenski's and Newman's methods were more likely to detect sarcopenia than Baumgartner's method (both P < 0.005). Patients were further divided into three subgroups: (i) patients classified in all indexes (n = 8), (ii) patients classified in Baumgartner's (sarcopenic; n = 27), and (iii) patients classified in both Newman's and Studenski's methods (sarcopenic obesity; n = 31). Comparing body composition among groups, all sarcopenic groups presented lower total lean mass compared with non-sarcopenic patients, whereas sarcopenic obese patients had higher total lean mass than lean sarcopenic patients. Conclusions Our results demonstrate that the prevalence of sarcopenia in overweight/obese patients is similar to lean sarcopenic patients when other methods are considered. In patients with higher BMI, Studenski's method seems to be more feasible to detect sarcopenia. (AU) | |
| Processo FAPESP: | 15/22814-5 - Câncer e coração: novos paradigmas de diagnóstico e tratamento |
| Beneficiário: | Carlos Eduardo Negrão |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 16/24306-0 - O efeito da Neprilisina (LCZ696) sobre a tolerância ao exercício, vasodilatação muscular, força muscular e composição corporal em pacientes com insuficiência cardíaca |
| Beneficiário: | Marcelo Rodrigues dos Santos |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |