Assessing the Metabolic Impact of Ground Chia Seed in Overweight and Obese Prepubescent Children: Results of a Double-Blind Randomized Clinical Trial

Autor(es):Mostrar menos -

da Silva, Camila Saran ^[1] ; Monteiro, Camila Ribeiro de Arruda ^[1] ; da Silva, Guilherme Henrique Fagundes ^[1] ; Sarni, Roseli Oselka Sacardo ^[1] ; Souza, Fabiola Isabel Suano ^[1] ; Feder, David ^[1] ; Messias, Marcia Cristina Fernandes ^[2] ; Carvalho, Patricia de Oliveira ^[2] ; Alberici, Rosana M. ^[3] ; Cunha, Ildenize B. S. ^[3] ; Eberlin, Marcos N. ^[3] ; Rosa, Paulo Cesar Pires ^[4] ; Fonseca, Fernando Luiz Affonso ^{[1, 5]}

Afiliação do(s) autor(es)

^[1] ABC Med Univ Ctr, FMABC, Dept Clin Anal, Santo Andre, SP - Brazil

^[2] USF, Lab Multidisciplinary Res, Braganca Paulista, SP - Brazil

^[3] Univ Estadual Campinas, Inst Chem, ThoMSon Mass Spectrometry Lab, Campinas, SP - Brazil

^[4] Univ Estadual Campinas, UNICAMP, Dept Pharmaceut Sci, Campinas, SP - Brazil

^[5] Fed Univ SP, Dept Pharmaceut Sci, Diadema, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF MEDICINAL FOOD; v. 23, n. 3 JAN 2020.
• Citações Web of Science: 1

Resumo

Childhood obesity is a medical condition of major public health concern. Chia seeds are used to treat certain noncommunicable diseases, and they are rich in omega-3 fatty acids, which contribute to the absorption of vitamins. A randomized double-blind clinical trial of 30 obese children was performed. The sample was composed of prepubertal 5- to 10-year-old children of both sexes with body mass indexes equal to or above the 95th percentile who were recruited through the Pediatric Department of the Faculdade de Medicina do ABC. Blood samples were drawn, the children were weighed and measured, and a 24-h dietary recall was obtained before and after the treatment. Not only were significant differences observed for fibrinogen (P = .011) but a correlation between the changes in markers and the presence of fibers was also observed for two inflammatory parameters: tumor necrosis factor-alpha (P = .027) and nuclear factor-kappa beta (P = .059). These results indicate that chia seeds may have anti-inflammatory effects related to their fiber content in the context of childhood obesity. (AU)

• Processo FAPESP: 15/26452-0 - Avaliação do estresse oxidativo em crianças obesas com tratamento de semente de Chia (Salvia hispânica) e sua implicação sobre a vitamina E
• Beneficiário: Camila Ribeiro de Arruda Monteiro
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica