Antimicrobials for food and feed; a bacteriocin perspective

Autor(es)

O'Connor, Paula M. ^{[1, 2]} ; Kuniyoshi, Tais M. ^{[1, 3]} ; Oliveira, Ricardo P. S. ^[3] ; Hill, Colin ^{[2, 4]} ; Ross, Reynolds Paul ^{[2, 4]} ; Cotter, Paul D. ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] TEAGASC, Food Res Ctr, Fermoy, Cork - Ireland

^[2] Univ Coll Cork, APC Microbiome Ireland, Cork - Ireland

^[3] Univ Sao Paulo, Fac Pharmaceut Sci, Biochem & Pharmaceut Technol Dept, Av Lineu Prestes 580, BR-05508900 Sao Paulo - Brazil

^[4] Univ Coll Cork, Sch Microbiol, Cork - Ireland

• Tipo de documento: Artigo de Revisão
• Fonte: CURRENT OPINION IN BIOTECHNOLOGY; v. 61, p. 160-167, FEB 2020.
• Citações Web of Science: 2

Resumo

Bacteriocins are natural antimicrobials that have been consumed via fermented foods for millennia and have been the focus of renewed efforts to identify novel bacteriocins, and their producing microorganisms, for use as food biopreservatives and other applications. Bioengineering bacteriocins or combining bacteriocins with multiple modes of action (hurdle approach) can enhance their preservative effect and reduces the incidence of antimicrobial resistance. In addition to their role as food biopreservatives, bacteriocins are gaining credibility as health modulators, due to their ability to regulate the gut microbiota, which is strongly associated with human wellbeing. Indeed the strengthening link between the gut microbiota and obesity make bacteriocins ideal alternatives to Animal Growth Promoters (AGP) in animal feed also. Here we review recent advances in bacteriocin research that will contribute to the development of functional foods and feeds as a consequence of roles in food biopreservation and human/animal health. (AU)

• Processo FAPESP: 18/04385-8 - Construção de uma linhagem recombinante produtora de pediocina a partir de resíduo agroindustrial
• Beneficiário: Ricardo Pinheiro de Souza Oliveira
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 15/24777-0 - Otimização da produção de pediocina A por Pediococcus pentosaceus ATCC 43200
• Beneficiário: Taís Mayumi Kuniyoshi
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 18/02519-7 - Expressão heteróloga da pediocina e seu efeito sobre Listeria spp. e na população da microbiota intestinal humana
• Beneficiário: Taís Mayumi Kuniyoshi
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado