Effect of perioperative hyperglycemia on surgical site infection in abdominal surgery: A prospective cohort study

Autor(es)

Bellusse, Gislaine Cristhina ^[1] ; Ribeiro, Julio Cesar ^[1] ; Martins de Freitas, Isabel Cristina ^[2] ; Galvao, Cristina Maria ^[3]

Afiliação do(s) autor(es)

^[1] Univ Franca, Franca, SP - Brazil

^[2] Univ Sao Paulo, Ribeirao Preto Coll Nursing, Epidemiol Ctr, Ribeirao Preto, SP - Brazil

^[3] Univ Sao Paulo, Ribeirao Preto Coll Nursing, Ave Bandeirantes 3900, Campus Univ Monte Alegre, BR-14040902 Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: AMERICAN JOURNAL OF INFECTION CONTROL; v. 48, n. 7, p. 781-785, JUL 2020.
• Citações Web of Science: 0

Resumo

Background: Surgical site infection (SSI) remains one of the most frequent complications in abdominal surgery, and hyperglycemia prevention is recommended as a measure to reduce this type of infection. The aims of this study were to estimate the incidence of SSI and to identify the effect of perioperative hyperglycemia on the incidence of this type of infection in patients undergoing abdominal surgery. Methods: We enrolled 484 abdominal surgery patients >= 18 years of age, recruited between July 2016 and May 2017. Data were collected through structured interviews and patient assessments in the perioperative period and at the surgical outpatient clinic (30th day after surgery). Crude and adjusted models were built to identify the effect of hyperglycemia on SSI. Results: The incidence rate of SSI was 20.25%. The attributable fraction for patients exposed to hyperglycemia was 60%. In the multivariable analysis, patients with hyperglycemia, at the end of the surgery and 12 hours later, were more likely to develop this type of infection (relative risk = 1.89 and 2.17, respectively). Conclusions: Perioperative hyperglycemia was identi fied as an independent risk factor for SSI. The evidence generated reinforces the importance of proper glycemic control management in the perioperative period for the prevention of SSI. (C) 2019 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. (AU)

• Processo FAPESP: 15/24274-8 - Efeito da hipotermia e da hiperglicemia sobre a incidência de infecção de sítio cirúrgico em cirurgias gastrointestinais: estudo de coorte
• Beneficiário: Cristina Maria Galvão
• Modalidade de apoio: Auxílio à Pesquisa - Regular