The Addition of Propylene Glycol Alginate to a Fluoride Solution to Control Enamel Wear: An in situ Study

Autor(es)

Sakae, Leticia Oba ^[1] ; Niemeyer, Samira Helena ^[2] ; Cardoso Bezerra, Savio Jose ^[1] ; Borges, Alessandra Buhler ^[3] ; Turssi, Cecilia Pedroso ^[4] ; Scaramucci, Tais ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Dent, Dept Restorat Dent, Av Prof Lineu Prestes 2227, BR-05508000 Sao Paulo, SP - Brazil

^[2] Univ Bern, Sch Dent Med, Dept Restorat Prevent & Pediat Dent, Bern - Switzerland

^[3] Sao Paulo State Univ, Inst Sci & Technol, Dept Restorat Dent, UNESP, Sao Jose Dos Campos - Brazil

^[4] Sao Leopoldo Mandic Res Inst, Div Cariol & Restorat Dent, Campinas - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Caries Research; v. 54, n. 5-6 NOV 2020.
• Citações Web of Science: 0

Resumo

The aim of this study was to evaluate the protective effect of propylene glycol alginate (PGA) associated with sodium fluoride (NaF) against enamel erosion and erosion-abrasion. A 4-phase, split-mouth, double-blind, crossover in situ trial was conducted with the following solutions: F + PGA (225 ppm F- + 0.1% PGA), F (225 ppm F-), F + Sn (225 ppm F- + SnCl2, 800 ppm Sn2+), and negative control (distilled water). In each phase, 12 subjects wore removable mandibular appliances containing 4 enamel specimens, which were submitted either to erosion or to erosion-abrasion challenges for 5 days. Acquired salivary pellicle was formed in situ for 2 h. Erosion-abrasion consisted of acid challenge (1% citric acid solution, pH 2.3, 5 min, 4x/day), exposure to saliva in situ (2 h, 4x/day), brushing (5 s, total 2 min exposure to the slurry), and treatment with the solutions (2 min, 2x/day). For erosion, the same procedures were performed, without brushing. At the end, surface loss (SL; in mu m) was evaluated by means of optical profilometry. KOH-soluble fluoride was quantified for erosion-only groups using extra specimens. For both challenges, the SL values found for F + PGA did not differ significantly from those of F and the negative control, and the SL value shown for F + Sn was significantly the lowest. Erosion-abrasion promoted significantly higher SL values than erosion. KOH-soluble fluoride analysis showed that F + Sn had a higher fluoride concentration in comparison with the negative control and F, while F + PGA did not differ from any of the other groups. In conclusion, PGA was not able to improve the protective effect of NaF against erosive enamel wear. (AU)

• Processo FAPESP: 17/09408-3 - Avaliação in situ do efeito anti-erosivo da associação entre o fluoreto de sódio e o propileno glicol alginato
• Beneficiário: Letícia Oba Sakae
• Modalidade de apoio: Bolsas no Brasil - Mestrado