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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Addition of Propylene Glycol Alginate to a Fluoride Solution to Control Enamel Wear: An in situ Study

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Author(s):
Sakae, Leticia Oba [1] ; Niemeyer, Samira Helena [2] ; Cardoso Bezerra, Savio Jose [1] ; Borges, Alessandra Buhler [3] ; Turssi, Cecilia Pedroso [4] ; Scaramucci, Tais [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Sch Dent, Dept Restorat Dent, Av Prof Lineu Prestes 2227, BR-05508000 Sao Paulo, SP - Brazil
[2] Univ Bern, Sch Dent Med, Dept Restorat Prevent & Pediat Dent, Bern - Switzerland
[3] Sao Paulo State Univ, Inst Sci & Technol, Dept Restorat Dent, UNESP, Sao Jose Dos Campos - Brazil
[4] Sao Leopoldo Mandic Res Inst, Div Cariol & Restorat Dent, Campinas - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Caries Research; v. 54, n. 5-6 NOV 2020.
Web of Science Citations: 0
Abstract

The aim of this study was to evaluate the protective effect of propylene glycol alginate (PGA) associated with sodium fluoride (NaF) against enamel erosion and erosion-abrasion. A 4-phase, split-mouth, double-blind, crossover in situ trial was conducted with the following solutions: F + PGA (225 ppm F- + 0.1% PGA), F (225 ppm F-), F + Sn (225 ppm F- + SnCl2, 800 ppm Sn2+), and negative control (distilled water). In each phase, 12 subjects wore removable mandibular appliances containing 4 enamel specimens, which were submitted either to erosion or to erosion-abrasion challenges for 5 days. Acquired salivary pellicle was formed in situ for 2 h. Erosion-abrasion consisted of acid challenge (1% citric acid solution, pH 2.3, 5 min, 4x/day), exposure to saliva in situ (2 h, 4x/day), brushing (5 s, total 2 min exposure to the slurry), and treatment with the solutions (2 min, 2x/day). For erosion, the same procedures were performed, without brushing. At the end, surface loss (SL; in mu m) was evaluated by means of optical profilometry. KOH-soluble fluoride was quantified for erosion-only groups using extra specimens. For both challenges, the SL values found for F + PGA did not differ significantly from those of F and the negative control, and the SL value shown for F + Sn was significantly the lowest. Erosion-abrasion promoted significantly higher SL values than erosion. KOH-soluble fluoride analysis showed that F + Sn had a higher fluoride concentration in comparison with the negative control and F, while F + PGA did not differ from any of the other groups. In conclusion, PGA was not able to improve the protective effect of NaF against erosive enamel wear. (AU)

FAPESP's process: 17/09408-3 - In situ evaluation of the anti-erosive effect of the association between sodium fluoride and propylene glycol alginate
Grantee:Letícia Oba Sakae
Support Opportunities: Scholarships in Brazil - Master