Current Knowledge on Snake Dry Bites

Autor(es)

Pucca, Manuela B. ^[1] ; Knudsen, Cecilie ^{[2, 3]} ; S. Oliveira, Isadora ^[4] ; Rimbault, Charlotte ^[2] ; A. Cerni, Felipe ^[4] ; Wen, Fan Hui ^[5] ; Sachett, Jacqueline ^{[6, 7]} ; Sartim, Marco A. ^{[8, 9]} ; Laustsen, Andreas H. ^[2] ; Monteiro, Wuelton M. ^{[6, 8]}

Afiliação do(s) autor(es)

^[1] Univ Fed Roraima, Sch Med, BR-69310000 Boa Vista, Roraima - Brazil

^[2] Tech Univ Denmark, Dept Biotechnol & Biomed, DK-2800 Lyngby - Denmark

^[3] Bioporto Diagnost AS, DK-2900 Hellerup - Denmark

^[4] Univ Sao Paulo, Dept Biomol Sci, Sch Pharmaceut Sci Ribeirao Preto, BR-14049900 Ribeirao Preto, SP - Brazil

^[5] Butantan Inst, BR-05503900 Sao Paulo - Brazil

^[6] Amazonas State Univ, Sch Hlth Sci, Dept Med & Nursing, BR-69065001 Manaus, Amazonas - Brazil

^[7] Alfredo da Matta Fdn, Dept Teaching & Res, BR-69065130 Manaus, Amazonas - Brazil

^[8] Dr Heitor Vieira Dourado Trop Med Fdn, Dept Teaching & Res, BR-69040000 Manaus, Amazonas - Brazil

^[9] Amazonas Fed Univ, Inst Biol Sci, BR-69067005 Manaus, Amazonas - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: TOXINS; v. 12, n. 11 NOV 2020.
• Citações Web of Science: 1

Resumo

Snake `dry bites' are characterized by the absence of venom being injected into the victim during a snakebite incident. The dry bite mechanism and diagnosis are quite complex, and the lack of envenoming symptoms in these cases may be misinterpreted as a miraculous treatment or as proof that the bite from the perpetrating snake species is rather harmless. The circumstances of dry bites and their clinical diagnosis are not well-explored in the literature, which may lead to ambiguity amongst treating personnel about whether antivenom is indicated or not. Here, the epidemiology and recorded history of dry bites are reviewed, and the clinical knowledge on the dry bite phenomenon is presented and discussed. Finally, this review proposes a diagnostic and therapeutic protocol to assist medical care after snake dry bites, aiming to improve patient outcomes. (AU)

• Processo FAPESP: 17/14035-1 - Melhoramento de fragmentos de anticorpos humanos (scFVs) específicos para peçonhas animais
• Beneficiário: Felipe Augusto Cerni
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 17/03580-9 - Avaliação bioquímica, estrutural e funcional de uma fosfodiesterase da peçonha de Crotalus durissus collilineatus
• Beneficiário: Isadora Sousa de Oliveira
• Modalidade de apoio: Bolsas no Brasil - Doutorado