Effects of Acetogenins fromAnnona coriaceaon thein VitroReactions of Photosynthesis

Autor(es)

Pasqualotto Severino, Vanessa Gisele ^[1] ; Souza Simao, Jorge Luiz ^[1] ; Moraes Junqueira, Joao Gabriel ^[2] ; de Carvalho, Ana Calheiros ^[3] ; King-Diaz, Beatriz ^[4] ; Lotina-Hennsen, Blas ^[4] ; Terezan, Ana Paula ^[1] ; Moura Veiga, Thiago Andre ^[3]

Afiliação do(s) autor(es)

^[1] Univ Fed Goias UFG, Inst Quim, BR-74690900 Goiania, Go - Brazil

^[2] Univ Fed Sao Carlos UFSCar, Dept Quim, BR-13565905 Sao Carlos, SP - Brazil

^[3] Univ Fed Sao Paulo UNIFESP, Dept Quim, BR-09972270 Diadema, SP - Brazil

^[4] Univ Nacl Autonoma Mexico, Fac Quim, Dept Bioquim, Ciudad Univ, Mexico City 04510, DF - Mexico

• Tipo de documento: Artigo Científico
• Fonte: CHEMISTRY & BIODIVERSITY; v. 17, n. 11 NOV 2020.
• Citações Web of Science: 1

Resumo

Our search for candidates for photosynthesis inhibitors is allowing us to report the effect of two acetogenins identified inAnnona coriaceaMart. leaves, ACG-A and ACG-B, a non-adjacent bis-THF and a mono-THF types, respectively. This is an important class of natural products which presents biological properties such as anticancer, neurotoxic, larvicidal and insecticidal. However, this is only the second report associated to its herbicidal activity. Their mechanisms of action on the light reactions of the photosynthesis were elucidated by polarographic techniques. Compounds inhibited the noncyclic electron transport on basal, phosphorylating, and uncoupled conditions from H2O to methyl viologen (MV); therefore, they act as Hill reaction inhibitors. Studies on fluorescence of chlorophyll a (ChLa) indicated that they inhibited the acceptor side of PSII between P680 and PQ-pool, exactly as the commercial herbicide DCMU does. (AU)

• Processo FAPESP: 10/51313-0 - Obtenção de substâncias fitotóxicas de espécies vegetais presentes em solos minerais da Mina do Sossego - PA com ação fitoremediadoras e controle ambiental
• Beneficiário: Thiago André Moura Veiga
• Modalidade de apoio: Auxílio à Pesquisa - Parceria para Inovação Tecnológica - PITE