Phytotoxic Neocassane Diterpenes from Eragrostis plana

Autor(es)

Klein Hendges, Ana Paula P. ^[1] ; dos Santos, Elaine Fernanda ^[1] ; Teixeira, Sirlei D. ^[2] ; Santana, Francielli S. ^[1] ; Trezzi, Michelangelo M. ^[3] ; Batista, Andrea N. L. ^[4] ; Batista Jr, Joao M. ; de Lima, Vanderlei A. ^[2] ; Marques, Francisco de Assis ^[1] ; Sales Maia, Beatriz Helena L. N. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Parana, Dept Chem, BR-81530900 Curitiba, Parana - Brazil

^[2] Fed Technol Univ Parana, Dept Chem, BR-85503390 Pato Branco, PR - Brazil

^[3] Fed Technol Univ Parana, Dept Agr Sci, BR-85503390 Pato Branco, PR - Brazil

^[4] Fluminense Fed Univ, Chem Inst, Dept Organ Chem, BR-24020141 Niteroi, RJ - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Natural Products; v. 83, n. 12, p. 3511-3518, DEC 24 2020.
• Citações Web of Science: 0

Resumo

Five new neocassane-like diterpenes (1-5) were isolated from the roots of Eragrostis plana. Their structures were elucidated by spectroscopic data, and the absolute configurations of the representative compounds neocassa-12(17),15-dien-3-one (2) and neocassa-12(13),15-diene-3,14-dione (5) were assigned by vibrational circular dichroism. The phytotoxic activity of compounds 3, 4, and 5 was evaluated against the germination and growth of Ipomoea grandifolia and Euphorbia heterophylla. Compound 4 exhibited the most potent activity for growth variables, resulting in the smallest radicle length of I. grandifolia and in the smallest aerial part length of E. heterophylla. Compound 5 reduced the germination speed index more effectively than the herbicide glyphosate (Roundup). (AU)

• Processo FAPESP: 14/25222-9 - Espectroscopia quiróptica vibracional na caracterização estereoquímica de pequenas moléculas e macromoléculas
• Beneficiário: João Marcos Batista Junior
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores