Nanotechnology as a tool for detection and treatment of arbovirus infections

Autor(es)

Duarte, Jonatas Lobato ^[1] ; Di Filippo, Leonardo Delello ^[1] ; Sousa Araujo, Victor Hugo ^[1] ; de Faria Mota Oliveira, Anna Eliza Maciel ^[2] ; Cavalcante de Araujo, Jennifer Thayanne ^[1] ; da Rocha Silva, Flavia Benini ^[1] ; Pinto, Mara Cristina ^[1] ; Chorilli, Marlus ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ UNESP, Sch Pharmaceut Sci, Rodovia Araraquara Jau, Km 01-S-N Campos Vile, BR-14800903 Araraquara, SP - Brazil

^[2] Fed Univ Amapa UNIFAP, Dept Hlth & Biol Sci, Rodovia Juscelino Kubitschek, Km 02, Jardim Marco Z, BR-68903361 Macapa, AP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Acta Tropica; v. 216, APR 2021.
• Citações Web of Science: 0

Resumo

Arboviruses are medically important viruses that cause high rates of infection all over the world. In addition, the severity of the symptoms and the inadequate diagnostic methods represent a challenge far beyond eradicating the vector. The lack of specific treatments for arbovirus infections reflects the imminent need for new research for safe and efficient medicines to treat these infections. Nanotechnology is an innovative approach currently used as a platform for developing new treatments, thus improving the biopharmaceutical properties of drugs. It can also be applied to the development of diagnostic devices, improving their detection capacity. The purpose of this paper is to review recent research on the use of nanotechnology for developing new treatments and detection devices for arbovirus infections. Interestingly, it was found that only a few studies report on the use of nano technology to treat arbovirus infections and that most of these reports focus on the fabrication of diagnostic tools. Also, some papers report on the use of nanotechnology for the development of vaccines, which in association with mosquito eradication programs could effectively reduce the high rates of infections by these viruses. (AU)

• Processo FAPESP: 18/18488-3 - Avaliação do potencial de carreadores lipídicos nanostruturados funcionalizados com bevacizumab para veiculação de docetaxel no tratamento de glioblastoma
• Beneficiário: Leonardo Delello Di Filippo
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 19/25125-7 - Nanoemulsões contendo terpenos como potenciais larvicidas e repelentes contra Aedes aegypti (Linnaeus, 1762)
• Beneficiário: Jonatas Lobato Duarte
• Modalidade de apoio: Bolsas no Brasil - Doutorado