| Texto completo | |
| Autor(es): |
Pereira, Amanda Gomes
[1]
;
Costa, Nara Aline
[2]
;
Gut, Ana Lucia
[1]
;
Azevedo, Paula Schmidt
[1]
;
Tanni, Suzana Erico
[1]
;
Zornoff, Leonardo Antonio Mamede
[1]
;
de Paiva, Sergio Alberto Rupp
[1]
;
Polegato, Bertha Furlan
[1]
;
Minicucci, Marcos Ferreira
[1]
Número total de Autores: 9
|
| Afiliação do(s) autor(es): | [1] UNESP Univ Estadual Paulista, Botucatu Med Sch, Dept Internal Med, Botucatu, SP - Brazil
[2] Univ Fed Goias, Fac Nutr, UFG, Goiania, Go - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | CLINICAL NUTRITION ESPEN; v. 42, p. 361-365, APR 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
Background: The purpose of this study was to evaluate urea to albumin ratio (UAR) as predictor of mortality in patients with septic shock. Methods: We included all individuals aged >= 18 years, with the diagnosis of septic shock at Intensive Care Unit (ICU) admission. Laboratorial and clinical data was recorded within the first 24 h of the patient's admission. Serum urea and albumin concentration were used for UAR calculation. All patients were followed during their ICU stay and the mortality rate was recorded. Results: 222 patients were included in the analysis; the mean age was 62.3 +/- 15.1 years and 66% were male. Mortality rate during the ICU stay was 59.9% and the median UAR was 40.7 (24.5-66.1). The UAR was also higher in patients who died in the ICU and was positively correlated with APACHE II, SOFA score and CRP. The ROC ICU mortality development (AUC: 0.617; CI 95%: 0.541-0.693; p: 0.003) at the cutoff of >= 47.25. Furthermore, UAR values were associated with ICU mortality when adjusted by age, sex and APACHE II (OR: 1.011; CI95%:1.000-1.022; p = 0.043) and when adjusted by lactate (OR: 1.014; CI95%:1.003-1.024; p = 0.009). Conclusions: Our data suggest that UAR could play a role as predictor of ICU mortality in patients with septic shock. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. (AU) | |
| Processo FAPESP: | 17/21554-5 - Influência da suplementação de tiamina no estresse oxidativo, metabolismo energético e mortalidade em pacientes com choque séptico |
| Beneficiário: | Amanda Gomes Pereira |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 14/17262-0 - Influência do zinco, do cobre e dos polimorfismos do gene da superóxido dismutase 1 na mortalidade de pacientes com choque séptico |
| Beneficiário: | Marcos Ferreira Minicucci |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |