ANTIOXIDANT NAPHTHOQUINONES OF Sinningia reitzii FROM SANTA CATARINA STATE, BRAZIL

Autor(es)

Winiewski, Vanessa ^[1] ; Silva, Adson S. ^[1] ; Alvarez, Kattleen D. C. ^[2] ; de Sa, Eduardo L. ^[1] ; Salvador, Marcos J. ^[2] ; Stefanello, Maria Elida A. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Parana, Dept Quim, BR-81530900 Curitiba, Parana - Brazil

^[2] Univ Estadual Campinas, Inst Biol, Dept Biol Vegetal, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Química Nova; v. 44, n. 3, p. 284-287, 2021.
• Citações Web of Science: 1

Resumo

Sinningia reitzii (Hoehne) L. E. Skog (Gesneriaceae) is a subshrub native to Brazil, where it is distributed in two disjunctive populations around the 26°S and 23°S parallels. In this work, tubers of plants from the wild population growing at the 26°S parallel (Santa Catarina state) yielded two new naphthoquinones, 5,6-dihydroxy-7-methoxy-a-dunnione and 8-hydroxy-6,7-dimethoxy-a-dunnione. Three known compounds were also isolated: 6,8-dihydroxy-7-methoxy-a-dunnione, 5-hydroxy-6,7-dimethoxy-a-dunnione, and 6,8-dihydroxy-7-methoxy-2-O-methyldunniol. The naphthoquinones 6,8-dihydroxy-7-methoxy-2-O-methyldunniol, 6,8-dihydroxy-7-methoxy-a-dunnione, and 5,6-dihydroxy-7-methoxy-a-dunnione displayed antioxidant activity in the ORAC-FL method, with values of relative trolox equivalent in the range of 1.39-4.83 mmol g-1. (AU)

• Processo FAPESP: 15/03726-8 - Estudo químico e biológico integrado para a busca de substâncias bioativas em espécies vegetais* e desenvolvimento de procedimentos analíticos. *(Amaranthaceae, Gesneriaceae, Myrtaceae e Annonaceae)
• Beneficiário: Marcos José Salvador
• Modalidade de apoio: Auxílio à Pesquisa - Regular