Techno-economical optimization of uvaia (Eugenia pyriformis) extraction using supercritical fluid technology

Autor(es)

Klein, Elissandro Jair ^[1] ; Nunes Carvalho, Pedro Ivo ^[2] ; Nathia-Neves, Grazielle ^[2] ; Vardanega, Renata ^{[2, 3]} ; Meireles, M. Angela A. ^[2] ; da Silva, Edson Antonio ^[4] ; Adeodato Vieira, Melissa Gurgel ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Sch Chem Engn, UNICAMP, Albert Einstein Ave 500, BR-13083852 Campinas, SP - Brazil

^[2] Univ Estadual Campinas, Sch Food Engn, LASEFI Dept Food Engn, UNICAMP, Monteiro Lobato St 80, BR-13083862 Campinas, SP - Brazil

^[3] Entourage Phytolab, Tabapua St 111, BR-04533010 Sao Paulo, SP - Brazil

^[4] Western Parana State Univ, Ctr Engn & Exact Sci, Fac St 645, BR-85903000 Toledo, Parana - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF SUPERCRITICAL FLUIDS; v. 174, AUG 2021.
• Citações Web of Science: 0

Resumo

This work presents an economic evaluation of supercritical fluid extraction (SFE) process from uvaia leaves. Extractions were performed at a previously optimized condition of pressure (200 bar) and temperature (60 degrees C) and were evaluated with the addition of 5% of two different co-solvents (ethyl acetate and ethanol). A scale-up study was performed by adopting constant values for the solvent to feed mass ratio (S/F) and the extraction time as criteria. Two different scales were assessed: 5-fold and 10-fold (vessel volume and mass due to the constant bed density). An economic evaluation using SuperPro Designer 8.5 (R) to estimate the cost of manufacturing (COM) by testing 3 different scenarios was also performed. The addition of co-solvents resulted in lower estimated production costs, and the addition of 5% (w/w) of ethanol showed the best results among the conditions evaluated. The COM values are in a range from 622.9 to 1102.6 US\$/kg extract. (AU)

• Processo FAPESP: 19/07596-2 - Perfil de bioatividade de extratos brutos de Eugenia pyriformis usando metabolômica de 1H RMN e perfil quadruplo de alta resolução de alfa-amilase/alfa-glucosidase/PTP1B/antioxidante combinados com HPLC-PDA-HRMS-SPE-NMR
• Beneficiário: Elissandro Jair Klein
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
• Processo FAPESP: 15/22952-9 - Obtenção e purificação de ± e ß-amirina a partir de folhas de Uvaia (Eugenia pyriformis Cambess)
• Beneficiário: Elissandro Jair Klein
• Modalidade de apoio: Bolsas no Brasil - Doutorado