Can the insecticide Imidacloprid affect the health of the Neotropical freshwater fish Astyanax altiparanae (Teleostei: Characidae)?

Autor(es)

Almeida, Eryka Costa ^{[1, 2]} ; Passos, Larissa Souza ^[2] ; Vieira, Carlos Eduardo Delfino ^[3] ; Acayaba, Raphael Danna ^[4] ; Montagner, Cassiana Carolina ^[4] ; Pinto, Ernani ^[2] ; Martinez, Claudia Bueno dos Reis ^[3] ; Fonseca, Ana Lucia ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Itajuba, Nat Resources Inst, Ave BPS, BR-37500903 Itajuba, MG - Brazil

^[2] Univ Sao Paulo, Dept Clin & Toxicol Anal, Fac Pharmaceut Sci, Ave Prof Lineu Prestes, Bl 17, BR-05508900 Sao Paulo, SP - Brazil

^[3] Univ Estadual Londrina, Dept Physiol Sci, Lab Anim Ecophysiol, Rod Celso Garcia Cid, BR-86057970 Londrina, PR - Brazil

^[4] Univ Estadual Campinas, Environm Chem Lab, Inst Chem, Cidade Univ Zeferino Vaz, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 85, JUL 2021.
• Citações Web of Science: 0

Resumo

Female juveniles of the Neotropical fish Astyanax altiparanae were exposed for 96 h to four treatments containing the active ingredient from Imidacloprid (R) commercial formulation (IMI 1, IMI 2, IMI 3, and IMI 4) and to a control treatment (only dechlorinated tap water). Glutathione content, glutathione S-transferase activity, lipid peroxidation (LPO) and protein carbonylation levels, acetylcholinesterase (AChE) activity, and frequency of micronuclei and erythrocyte nuclear abnormalities (ENA) were measured in the fish. The muscle and gills were the most affected organs; their antioxidant defense was not enough to prevent oxidative damage (LPO) in the IMI 2 and IMI 4 treatment fish. IMI also inhibited AChE activity in the muscle (IMI 3 and IMI 4) and increased ENA frequency (IMI 4). IMI can affect the health of A. altiparanae in environmentally relevant concentrations, causing oxidative damage in different organs, neurotoxic effects in the muscle, and genotoxicity. (AU)

• Processo FAPESP: 20/00109-6 - Avaliação da toxicidade de cianopeptídeos em peixes para consumo humano provenientes de pisciculturas em tanques-rede
• Beneficiário: Larissa Souza Passos
• Modalidade de apoio: Bolsas no Brasil - Mestrado