Genomic Responses to Climate Change: Making the Most of the Drosophila Model

Autor(es)

Rodrigues, Murillo F. ^[1] ; Cogni, Rodrigo ^[2]

Afiliação do(s) autor(es)

^[1] Univ Oregon, Inst Ecol & Evolut, Eugene, OR 97403 - USA

^[2] Univ Sao Paulo, Dept Ecol, Inst Biosci, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: FRONTIERS IN GENETICS; v. 12, JUL 13 2021.
• Citações Web of Science: 0

Resumo

It is pressing to understand how animal populations evolve in response to climate change. We argue that new sequencing technologies and the use of historical samples are opening unprecedented opportunities to investigate genome-wide responses to changing environments. However, there are important challenges in interpreting the emerging findings. First, it is essential to differentiate genetic adaptation from phenotypic plasticity. Second, it is extremely difficult to map genotype, phenotype, and fitness. Third, neutral demographic processes and natural selection affect genetic variation in similar ways. We argue that Drosophila melanogaster, a classical model organism with decades of climate adaptation research, is uniquely suited to overcome most of these challenges. In the near future, long-term time series genome-wide datasets of D. melanogaster natural populations will provide exciting opportunities to study adaptation to recent climate change and will lay the groundwork for related research in non-model systems. (AU)

• Processo FAPESP: 16/01354-9 - Variação em clinas em genes do sistema imune de Drosophila melanogaster
• Beneficiário: Murillo Fernando Rodrigues
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 13/25991-0 - Ecologia genômica de insetos: adaptações ao clima e evolução de interações ecológicas
• Beneficiário: Rodrigo Cogni
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 17/06374-0 - Padrões globais de variação natural em genes imunes de Drosophila melanogaster
• Beneficiário: Murillo Fernando Rodrigues
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Mestrado
• Processo FAPESP: 17/02206-6 - Adaptações em clinas em Drosophila melanogaster
• Beneficiário: Rodrigo Cogni
• Modalidade de apoio: Bolsas no Exterior - Pesquisa