| Texto completo | |
| Autor(es): |
Otto, Paulo A.
[1]
Número total de Autores: 1
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| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Inst Biociencias, Dept Genet, Lab Genet Humana, Rua Matao 277, Cidade Univ, BR-05508090 Sao Paulo, SP - Brazil
Número total de Afiliações: 1
|
| Tipo de documento: | Artigo Científico |
| Fonte: | GENETICS AND MOLECULAR BIOLOGY; v. 44, n. 3 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
Abstract Besides reviewing the unusual case of sex-ratio in the lemming and presenting alternative analyses of general models in which the shift in the usual sex-ratio 1:1 is determined by autosomal or sex-linked mutant alleles, three novel models are presented, in which the shift on the progeny sex-ratio depends on the number of copies of a mutant allele present in the parental pair. The analysis of these models with additive effects shows that: 1) autosomal mutations that alter the usual sex-ratio are eliminated from the population; 2) mutations occurring on the X chromosome lead to an evolutionary stable 1:1 sex-ratio only if the mutation favors the production of males; when the mutant allele favors the production of females, however, females will prevail in the population, with a frequency dependent impact on δ (the deviation from the usual 0.5 proportion) ; for most of the range of possible values of δ the stable but extraordinary sex-ratio will vary from 1 male : 1 female to 1 male : 3 females or 1 male : 2 females approximately depending whether the mutant allele is randomly inactivated or not. (AU) | |
| Processo FAPESP: | 11/10877-1 - Modelos em genética de populações: aplicações em genética forense, genética da razão sexual e atraso do desenvolvimento larvar em insetos |
| Beneficiário: | Paulo Alberto Otto |
| Modalidade de apoio: | Bolsas no Exterior - Pesquisa |