ffects of the consumption of guarana on human health: A narrative revie

Autor(es)

Torres, Elizabeth A. F. S. ^[1] ; da C Pinaffi-Langley, Ana Clara ^[1] ; Figueira, Marcela de Souza ^[1] ; Cordeiro, Karina Silva ^[1] ; Negrao, Leonardo Dias ^[1] ; Soares, Maiara Jurema ^[1] ; da Silva, Cintia Pereira ^[1] ; Zsigovics Alfino, Maria Carolina ^[1] ; Sampaio, Geni Rodrigues ^[1] ; de Camargo, Adriano Costa ^[2]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, BR-01246904 Sao Paulo - Brazil

^[2] Univ Chile, Nutr & Food Technol Inst, Lab Antioxidants, Santiago 7830490 - Chile

• Tipo de documento: Artigo de Revisão
• Fonte: COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY; v. 21, n. 1 NOV 2021.
• Citações Web of Science: 1

Resumo

Guarana (Paullinia cupana) is a plant from the Amazon region with cultural importance. Despite its early ancestral use by indigenous tribes, the first reports regarding the benefits of guarana consumption for human health were published in the 19th century. Since then, the use of guarana seed in powder and extract forms has been studied for its diverse effects on human health, such as stimulating, anti-inflammatory, antioxidant, anticancer, hypocholesterolemic, and anti-obesity effects. These effects are attributed to the high content of bioactive compounds found in guarana seeds, especially methylxanthines and flavonoids. In fact, the Brazilian Food Supplement Law has officially acknowledged guarana as a source of bioactive compounds. The number and diversity of studies focused on guarana and human health are increasing; thus, organizing and describing the available evidence on guarana and its applications is necessary to provide a framework for future studies. In this narrative review, we have organized the available information regarding guarana and its potential effects on human health. Guarana produces unique fruits with great potential for human health applications. However, the available evidence lacks human studies and mechanistic investigations. Future studies should be designed considering its applicability to human health, including intake levels and toxicity studies. (AU)

• Processo FAPESP: 17/20039-0 - Efeitos do guaraná (Paullinia cupana) no metabolismo lipídico e bioacessibilidade de seus polifenóis em genes relacionados à absorção de colesterol em células Caco-2
• Beneficiário: Elizabeth Aparecida Ferraz da Silva Torres
• Modalidade de apoio: Auxílio à Pesquisa - Regular