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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

ffects of the consumption of guarana on human health: A narrative revie

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Author(s):
Torres, Elizabeth A. F. S. [1] ; da C Pinaffi-Langley, Ana Clara [1] ; Figueira, Marcela de Souza [1] ; Cordeiro, Karina Silva [1] ; Negrao, Leonardo Dias [1] ; Soares, Maiara Jurema [1] ; da Silva, Cintia Pereira [1] ; Zsigovics Alfino, Maria Carolina [1] ; Sampaio, Geni Rodrigues [1] ; de Camargo, Adriano Costa [2]
Total Authors: 10
Affiliation:
[1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, BR-01246904 Sao Paulo - Brazil
[2] Univ Chile, Nutr & Food Technol Inst, Lab Antioxidants, Santiago 7830490 - Chile
Total Affiliations: 2
Document type: Review article
Source: COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY; v. 21, n. 1 NOV 2021.
Web of Science Citations: 1
Abstract

Guarana (Paullinia cupana) is a plant from the Amazon region with cultural importance. Despite its early ancestral use by indigenous tribes, the first reports regarding the benefits of guarana consumption for human health were published in the 19th century. Since then, the use of guarana seed in powder and extract forms has been studied for its diverse effects on human health, such as stimulating, anti-inflammatory, antioxidant, anticancer, hypocholesterolemic, and anti-obesity effects. These effects are attributed to the high content of bioactive compounds found in guarana seeds, especially methylxanthines and flavonoids. In fact, the Brazilian Food Supplement Law has officially acknowledged guarana as a source of bioactive compounds. The number and diversity of studies focused on guarana and human health are increasing; thus, organizing and describing the available evidence on guarana and its applications is necessary to provide a framework for future studies. In this narrative review, we have organized the available information regarding guarana and its potential effects on human health. Guarana produces unique fruits with great potential for human health applications. However, the available evidence lacks human studies and mechanistic investigations. Future studies should be designed considering its applicability to human health, including intake levels and toxicity studies. (AU)

FAPESP's process: 17/20039-0 - Effects of guaraná (Paullinia cupana) on lipid metabolism and bioacessibility of its polyphenols in genes related to the absorption of cholesterol in Caco-2 cells
Grantee:Elizabeth Aparecida Ferraz da Silva Torres
Support Opportunities: Regular Research Grants