Chemical characterization of bioactive compounds of non-conventional food plants (NCFP) for the development of products with functional appeal

• Grant number: 20/08761-4
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2021
• End date: March 31, 2024
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Science
• Agreement: FAPEAM
• Principal Investigator: Glaucia Maria Pastore
• Grantee: Glaucia Maria Pastore
• Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated researchers: Edgar Aparecido Sanches ; Henrique Silvano Arruda ; Iramaia Angélica Neri Numa ; Jaqueline de Araújo Bezerra ; Lúcia Schuch Boeira ; Pedro Henrique Campelo Felix

Abstract

Feed is one of the most basic and primordial needs of the human being, since food not only ensures organic satiety for the physiological maintenance of the body, but also plays an important role in sociocultural constructions as well as the forms of organization of agriculture itself all around the world. In addition, the incidence of chronic non-communicable diseases (NCDs; metabolic syndromes, cardiovascular diseases, cancer and chronic respiratory diseases) resulting from increased consumption of processed energy rich in foods with a low content of bioactive micronutrients and sedentary and stressful lifestyles, significantly impact not only the food system on health but also the economy, equity and the environment. In parallel, epidemiological studies demonstrate that nutritional interventions with foods rich in polyphenols (eg.: flavonoids) can mitigate several comorbidities. Such evidence corroborates the central role of these compounds in redox status, inflammation and lipid profile, making them eligible for the maintenance of metabolic syndromes, cardiovascular and neurodegenerative disorders. Consequently, public authorities have been associated with the food industry, seeking to find meaningful and lasting solutions, without giving up contemporary facilities. Aligned with this concept, the food industries have been working to develop alternatives that meet the new demands for healthiness, aiming at the use of differentiated and quality ingredients with guaranteed origin, in addition to issues related to sustainability, social, ethical aspects and transparency in information. In view of this, the use of Brazilian biodiversity as well as the recovery of traditional knowledge associated with the consumption of vegetables, fruits, flowers or herbs that grow spontaneously in nature emerge as more sustainable and nutritionally adequate concepts to increase food sovereignty and nutritional security of the collective and consumption point of view. Despite the promise of metabolic health, additional mechanistic, experimental and clinical studies of bioactives and their metabolites are still needed to further elucidate their typology, bioavailability, metabolism and health effects. In this sense, unconventional food plants (NCFP) represent an important alternative for a more balanced, healthier and more sustainable diet, in addition to providing candidate bioactive compounds for the prevention and treatment of various diseases. Therefore, this project will keep the focus on valuing the biodiversity of Brazilian NCFPs where first, the intersection of the physical-chemical and functional chemical dimensions of the mapati (Pourouma cecropiifolia Mart) and the buxixus (Clidemia hirta and C. japurensis DC.) Will be contemplated. Then, our research efforts will be based on the technological potential of these species. Thus, alcoholic and non-alcoholic beverages based on these NCFPs will be developed and evaluated as to their functional potential, to meet the demand for new flavors and better quality of life added to the inherent advantages of the product. The proposed project will be a close research between researchers from UNICAMP, (FAPESP arm) and researchers from the Federal Institute of Education, Science and Technology of Amazonas, Campus-Manaus Zona Leste and Manaus-Centro and, the Federal University of Amazonas (arm FAPEAM), using mutual knowledge and research infrastructures. For all these purposes, the project will include six work packages, according to the research focus mentioned above. With this, it is expected that this partnership will unlock the functional potential of NCFP and provide the basis for a future industrial application of their bioactive compounds, in addition to generating scientific knowledge and high-impact technological development. (AU)

Scientific publications

(7)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ARRUDA, HENRIQUE SILVANO; LOPES ARAUJO, MARIA VITORIA; MAROSTICA JUNIOR, MARIO ROBERTO. Underexploited Brazilian Cerrado fruits as sources of phenolic compounds for diseases management: A review. FOOD CHEMISTRY: MOLECULAR SCIENCES, v. 5, p. 22-pg., 2022-11-23. (15/13320-9, 20/08761-4, 18/11069-5, 19/13465-8, 15/50333-1)

DE OLIVEIRA, WILLIARA QUEIROZ; NERI-NUMA, IRAMAIA ANGELICA; ARRUDA, HENRIQUE SILVANO; MCCLEMENTS, DAVID JULIAN; PASTORE, GLAUCIA MARIA. Encapsulation of flavonoids in foods for diabetics: The emerging paradigm for an effective therapy. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 127, p. 9-pg., 2022-07-31. (20/08761-4)

ARRUDA, HENRIQUE SILVANO; BORSOI, FELIPE TECCHIO; ANDRADE, AMANDA CRISTINA; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO. Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit (Annona crassiflora Mart.). PLANTS-BASEL, v. 12, n. 7, p. 39-pg., 2023-04-01. (15/13320-9, 15/50333-1, 19/13465-8, 20/08761-4, 18/11069-5)

BORSOI, FELIPE TECCHIO; NERI-NUMA, IRAMAIA ANGELICA; DE OLIVEIRA, WILLIARA QUEIROZ; DE ARAUJO, FABIO FERNANDES; PASTORE, GLAUCIA MARIA. Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: A mini-review. FOOD CHEMISTRY: MOLECULAR SCIENCES, v. 6, p. 14-pg., 2022-12-20. (20/15163-6, 20/08761-4)

ALEGRE, GABRIELA FABIANA SOARES; PASTORE, GLAUCIA MARIA. The emerging importance of NAD+ metabolome for nutrition and food sciences: A bibliometric analysis. FOOD BIOSCIENCE, v. 56, p. 11-pg., 2023-09-11. (20/08761-4)

ALEGRE, GABRIELA FABIANA SOARES; PASTORE, GLAUCIA MARIA. NAD plus Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health. CURRENT NUTRITION REPORTS, v. 12, n. 3, p. 20-pg., 2023-06-05. (20/08761-4)

ARRUDA, HENRIQUE SILVANO; SILVA, ERIC KEVEN; PASTORE, GLAUCIA MARIA; MAROSTICA, MARIO ROBERTO. Non-Thermal Supercritical Carbon Dioxide Processing Retains the Quality Parameters and Improves the Kinetic Stability of an Araticum Beverage Enriched with Inulin-Type Dietary Fibers. FOODS, v. 12, n. 13, p. 21-pg., 2023-07-01. (23/01876-9, 15/13320-9, 15/50333-1, 19/13465-8, 20/08761-4, 18/11069-5)