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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Effect of low-level laser therapy on the membrane induced by the Masquelet technique at an orthotopic site in rabbits

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Autor(es):
Figueroa Coris, Jeniffer Gabriela [1, 2] ; Rahal, Sheila Canevese [2] ; Fonseca-Alves, Carlos Eduardo [2] ; Mamprim, Maria Jaqueline [2] ; Inamassu, Leticia Rocha [2] ; de Abreu Sampaio, Alexandre Botelho [2] ; Kano, Washington Takashi [2] ; Mesquita, Luciane dos Reis [2] ; de Siqueira Silva Junior, Jose Ivaldo [1, 2]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Univ Estadual Paulista, UNESP, Postgrad Program Anim Biotechnol, Dept Vet Surg & Anim Reprod, Sch Vet Med & Anim Sc, Botucatu, SP - Brazil
[2] Univ Estadual Paulista, UNESP, Dept Vet Surg & Anim Reprod, Sch Vet Med & Anim Sci, Botucatu, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Acta Cirurgica Brasileira; v. 36, n. 10 2021.
Citações Web of Science: 0
Resumo

ABSTRACT Purpose: To evaluate the low-level laser therapy (LLLT) on the membrane induced by the Masquelet technique in rabbits. Methods: Twelve Norfolk rabbits at approximately 3 months of age were used. A 1-cm segmental defect was induced in both radii, which were filled with polymethylmethacrylate cylinder. LLLT was used postoperatively in the bone defect of one of the forelimbs every 48 hours for 15 days. Six rabbits were euthanatized on third and sixth postoperative weeks. Results: In both forelimbs, radiographs showed new bone growth from radius cut ends on the third postoperative week and more advanced stage on the sixth postoperative week. Ultrasound showed induced membrane one week after the surgery. Histologically, there were no significant differences in the semi-quantitative score of inflammation intensity, total number of blood vessels, bone metaplasia, and collagen. The average thicknesses were 2,050.17 and 1,451.96 μm for control membranes and 2,724.26 and 2,081.03 μm for irradiated membranes, respectively, on third and sixth postoperative weeks. Vascular endothelial growth factor A (VEGF-A) and platelet derived growth factor (PDGF) expression were present in the induced membranes of control and irradiated forelimbs, but there was no significant difference. Conclusions: Based on assessment methods, it was not possible to demonstrate the effect of LLLT on the induced membrane. (AU)

Processo FAPESP: 19/01750-0 - Efeito da irradiação com laser de baixa intensidade na qualidade de membrana induzida pela técnica de Masquelet em coelhos
Beneficiário:Jeniffer Gabriela Figueroa Coris
Modalidade de apoio: Bolsas no Brasil - Mestrado