Individualised prognosis for risk of developing abdominal obesity in the paediatric population

Autor(es)

Nascimento-Ferreira, Marcus Vinicius ^{[1, 2]} ; Berg, Gabriela ^[3] ; Gonzalez Zapata, Laura Ines ^[4] ; Ferreira De Moraes, Augusto Cesar ^{[1, 5, 6, 7]} ; Carvalho, Heraclito Barbosa ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Med, YCARE Youth Child & Cardiovasc Risk & Environm Re, Sao Paulo - Brazil

^[2] Fed Univ Tocantins, Hlth Phys Act & Behav Res Hlth BRA Grp, Miracema Do Tocantins, TO - Brazil

^[3] Univ Buenos Aires, Fac Farm & Bioquim, Inst Fisiopatol & Bioquim Clin INFIBIOC, Buenos Aires, DF - Argentina

^[4] Univ Antioquia, Sch Nutr & Dietet, Social & Econ Determinants Hlth & Nutr Res Grp, Medellin - Colombia

^[5] Univ Sao Paulo, Grad Program Publ Hlth, Dept Epidemiol, Sch Publ Hlth, Sao Paulo, SP - Brazil

^[6] Univ Sao Paulo, Grad Program Epidemiol, Sch Publ Hlth, Sao Paulo, SP - Brazil

^[7] Univ Texas Austin UTHlth, Sch Publ Hlth, Dept Epidemiol Human Genet & Environm Sci EHGES, Austin, TX - USA

• Tipo de documento: Artigo Científico
• Fonte: CLINICAL NUTRITION ESPEN; v. 45, p. 333-340, OCT 2021.
• Citações Web of Science: 0

Resumo

Aims: To develop and validate risk scores for predicting abdominal obesity in South American children and adolescents based on extrinsic and intrinsic variables. Methods: Children (n = 358) and adolescents (n = 369) from seven South American cities from the South American Youth Cardiovascular and Environmental (SAYCARE) Study. The primary outcome was abdominal obesity. Potential predictors were based on sociodemographic, maternal, environmental, and behavioural factors and nutritional status. In multilevel logistic models, associated variables were tested to build the scores, which were internally validated. Results: We identified 120 children and 98 adolescents who were abdominally obese. We found at least five variables associated with the outcome in children with unacceptable predictive capacity. However, in adolescents, we found that biological sex, age, maternal body mass index (BMI), active commuting by bike, soft drink consumption (for risk score A), and weight (for score B) can predict abdominal obesity. Both scores, A and B, showed acceptable performance in the ROC curve {[}areas under curve: 0.70 (95% CI: 0.56-0.82) and 0.95 (95% CI: 0.89-1.0 0), respectively]. Conclusion: The SAYCARE risk scores present accurate, individualised estimates for identifying adolescents who are at risk of developing abdominal obesity. However, these have not been externally validated. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 19/02617-1 - Novas fronteiras em saúde nutricional e cardiovascular pediátrica: Desenvolvimento de métodos para avaliar a dupla carga de má-nutrição e a saúde cardiovascular ideal em países de baixa-média renda - SAYCARE Cohort Study
• Beneficiário: Augusto César Ferreira de Moraes
• Modalidade de apoio: Bolsas no Brasil - Jovens Pesquisadores