Magnetic nanoparticles in biomedical applications: A review

Autor(es)

Materon, Elsa M. ^[1] ; Miyazaki, Celina M. ^[2] ; Carr, Olivia ^[1] ; Joshi, Nirav ^[1] ; Picciani, Paulo H. S. ^[3] ; Dalmaschio, Cleocir J. ^[4] ; Davis, Frank ^[5] ; Shimizu, Flavio M. ^[6]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sao Carlos Inst Phys, CP 369, BR-13560970 Sao Carlos, SP - Brazil

^[2] Univ Fed Sao Carlos, Dept Phys Chem & Math, Rod Joao Leme Santos, Km 110, BR-18052780 Sorocaba, SP - Brazil

^[3] Univ Fed Rio de Janeiro IMA UFRJ, Inst Macromol Prof Eloisa Mano, BR-21941598 Rio De Janeiro, RJ - Brazil

^[4] Univ Fed Espirito Santo, Dept Chem, BR-29075910 Vitoria, ES - Brazil

^[5] Univ Chichester, Dept Engn & Appl Design, Bognor Regis PO2 11HR, W Sussex - England

^[6] Univ Estadual Campinas, UNICAMP, Gleb Wataghin Inst Phys IFGW, Dept Appl Phys, BR-13083859 Campinas, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: APPLIED SURFACE SCIENCE ADVANCES; v. 6, DEC 2021.
• Citações Web of Science: 4

Resumo

Biomedical applications with emphasis on the design of smart materials, specifically magnetic nanoparticles (MNPs) are considered to have technological benefits because they can be manipulated using magnetic fields. Magnetic NPs have been widely used in hyperthermia, target drug delivery system, imaging, and extraction of biomolecules, postulating them also as an important tool in cancer treatment. Morphological structures of magnetic materials have drawn tremendous attention from diverse scientific fields due to their unique surface chemistry, nontoxicity, biocompatibility, and particularly their inducible magnetic moment. This review features recent research accomplishments made in the biomedical field using magnetic nanoparticles. The first part gives a comprehensive overview of magnetic nanoparticles in the treatment of chronic diseases and drug targeting. The second part includes the role of magnetic nanoparticles in electrochemical, optical-based immunoassays. The review also outlines the current challenges and future research perspectives for fostering advanced and high-performance magnetic nanoparticles in technological applications. (AU)

• Processo FAPESP: 18/22214-6 - Rumo à convergência de tecnologias: de sensores e biossensores à visualização de informação e aprendizado de máquina para análise de dados em diagnóstico clínico
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• Beneficiário: Niravkumar Jitendrabhai Joshi
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 16/00991-5 - Estudo da Interação de Enzimas de Detoxificação com Fármacos Quimioterápicos e sua relação com a Quimiorresistência
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