ATTERNED INTERFERENCE RADIATION FORCE FOR TRANSCRANIAL NEUROMODULATIO

Autor(es)

Kim, Young Hun ^{[1, 2]} ; Kang, Ki Chang ^{[1, 2]} ; Kim, Jeong Nyeon ^[1] ; Pai, Chi Nan ^{[1, 3]} ; Zhang, Yichi ^[1] ; Ghanouni, Pejman ^[4] ; Park, Kwan Kyu ^{[1, 2]} ; Firouzi, Kamyar ^[1] ; Khuri-Yakub, Burtus T. ^[1]

Afiliação do(s) autor(es)

^[1] Stanford Univ, Dept Elect Engn, EL Ginzton Lab, Stanford, CA 94305 - USA

^[2] Hanyang Univ, Mech Convergence Engn, Seoul - South Korea

^[3] Univ Sao Paulo, Dept Mechatron Engn, Polytech Sch, Sao Paulo - Brazil

^[4] Stanford Univ, Dept Radiol, Stanford, CA 94305 - USA

• Tipo de documento: Artigo Científico
• Fonte: ULTRASOUND IN MEDICINE AND BIOLOGY; v. 48, n. 3, p. 497-511, MAR 2022.
• Citações Web of Science: 0

Resumo

Compared with the conventional method of transcranial focused ultrasound stimulation using a single transducer or a focused beam, the compression and tensile forces are generated from the high-pressure gradient of a standing wave that can generate increased stimulation. We experimentally verified a neuromodulation system using patterned interference radiation force (PIRF) and propose a method for obtaining the magnitude of the radiation force, which is considered the main factor influencing ultrasound neuromodulation. The radiation forces generated using a single focused transducer and a standing wave created via two focused transducers were compared using simulations. Radiation force was calculated based on the relationship between the acoustic pressure, radiation force and time-averaged second-order pressure obtained using an acoustic streaming simulation. The presence of the radiation force was verified by measuring the time-averaged second-order pressure generated due to the radiation force, by using a glass tube. (E-mail: [e-mail]) (c) 2021 World Federation for Ultrasound in Medicine \& Biology. All rights reserved. (AU)

• Processo FAPESP: 18/00710-1 - Transdutor capacitivo microfabricado para tomografia de ultrassom
• Beneficiário: Chi Nan Pai
• Modalidade de apoio: Bolsas no Exterior - Pesquisa