Autor(es)

Castro dos Santos, Nidia C. ; Furukawa, Monique V. ; Oliveira-Cardoso, Ingrid ; Cortelli, Jose Roberto ; Feres, Magda ; Van Dyke, Thomas ; Rovai, Emanuel S.

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF PERIODONTAL RESEARCH; v. 57, n. 3, p. 13-pg., 2022-03-03.

Resumo

This review aimed to assess the impact of dietary omega-3 fatty acids as an adjunct to non-surgical periodontal treatment when compared with periodontal treatment alone on periodontal clinical parameters of periodontitis patients. We included only randomized clinical trials (RCTs) with at least 3-months follow-up of non-surgical periodontal therapy, in combination with dietary omega-3 fatty acids. The MEDLINE, EMBASE, and LILACS databases were searched for articles published up to October 2021. Random-effects meta-analyses were conducted to determine the change in clinical attachment level (CAL), probing pocket depth (PPD), bleeding on probing (BOP), and gingival index (GI) after therapy. Of the eight hundred eighty-four potentially relevant papers retrieved from the electronic databases, 10 RCTs were selected for qualitative analysis, and of these, 8 RCTs were included in meta-analysis. RCTs showed a significant PPD reduction/CAL gain associated with the use of omega-3 fatty acids. The pooled estimates revealed significant overall PPD reduction of 0.42 mm (95% CI 0.15, 0.68) and CAL gain 0.58 mm (95% CI 0.24, 0.92). In individuals with periodontitis, the use of omega-3 fatty acid dietary supplementation as an adjunct to non-surgical periodontal treatment can provide additional benefits in CAL gain and PPD reduction, compared with non-surgical periodontal treatment alone. (AU)

• Processo FAPESP: 20/05874-2 - Efeitos clínicos e microbiológicos da imunomodulação, associada ou não a antibióticos sistêmicos, no tratamento da periodontite
• Beneficiário: Magda Feres Figueiredo
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 20/05875-9 - Ômega-3 e aspirina, associados ou não a antibióticos sistêmicos, no tratamento periodontal: efeitos clínicos e sistêmicos, incluindo perfil imunológico por citometria de massa
• Beneficiário: Nidia Cristina Castro dos Santos
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 19/14846-5 - Avaliação do perfil proteômico salivar em pacientes diabéticos tipo 2 com periodontite
• Beneficiário: Emanuel da Silva Rovai
• Modalidade de apoio: Auxílio à Pesquisa - Regular