Re-emergence of mayaro virus and coinfection with chikungunya during an outbreak in the state of Tocantins/Brazil

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dos Santos Souza Marinho, Robson ; Duro, Rodrigo Lopes Sanz ; Bellini Caldeira, Debora ; Galinskas, Juliana ; Oliveira Mota, Manlio Tasso ; Hunter, James ; Rodrigues Teles, Maria da Aparecida ; de Padua Milagres, Flavio Augusto ; Sobhie Diaz, Ricardo ; Shinji Kawakubo, Fernando ; Vasconcelos Komninakis, Shirley

• Tipo de documento: Artigo Científico
• Fonte: BMC RESEARCH NOTES; v. 15, n. 1, p. 7-pg., 2022-08-03.

Resumo

Objective To perform a molecular screening to detect infections by the mayaro virus and possible coinfections with Chikungunya during an outbreak in the state of Tocantins/Brazil in 2017. Results Of a total 102 samples analyzed in this study, 6 cases were identified with simultaneous infection between mayaro and chikungunya viruses (5.88%). In these 6 samples, the mean Cycle threshold (Ct) for CHIKV was 26.87 (SD +/- 10.54) and for MAYV was 29.58 (SD +/- 6.34). The mayaro sequences generated showed 95-100% identity to other Brazilian sequences of this virus and with other MAYV isolates obtained from human and arthropods in different regions of the world. The remaining samples were detected with CHIKV monoinfection (41 cases), DENV monoinfection (50 cases) and coinfection between CHIKV/DENV (5 cases). We did not detect MAYV monoinfections. (AU)

• Processo FAPESP: 15/19343-0 - Metagenômica viral em indivíduos com diagnóstico tardio pelo HIV/AIDS
• Beneficiário: Shirley Cavalcante Vasconcelos
• Modalidade de apoio: Auxílio à Pesquisa - Regular