Long-term effects of COVID-19 in diabetic and non-diabetic patients

Autor(es)

Alberca, Ricardo Wesley ; Ramos, Yasmim Alefe Leuzzi ; Pereira, Natalli Zanete ; Beserra, Danielle Rosa ; Branco, Anna Claudia Calvielli Castelo ; Orfali, Raquel Leao ; Aoki, Valeria ; Duarte, Alberto Jose da Silva ; Sato, Maria Notomi

• Tipo de documento: Artigo Científico
• Fonte: FRONTIERS IN PUBLIC HEALTH; v. 10, p. 5-pg., 2022-08-15.

Resumo

The literature presents several reports of the impact of glycemic control and diabetes in the inflammatory and coagulatory response during coronavirus disease 2019 (COVID-19). Nevertheless, the long-term impact of the COVID-19 in diabetic patients is still to be explored. Therefore, we recruited 128 patients and performed a longitudinal analysis on COVID-19-associated biomarkers of patients with COVID-19, tree and 6 months after COVID-19 recovery and put into perspective the possible long-term complication generated after COVID-19. In our investigation, we failed to verify any long-term modification on inflammatory biomarkers, but detected an increase in the glycemia and glycated hemoglobin in patients without any pre-existing history or diagnosis of diabetes (non-diabetic patients). Although diabetic and non-diabetic patients presented elevated levels of glycated hemoglobin, the c-peptide test indicated a normal beta cell function in all patients. (AU)

• Processo FAPESP: 20/13148-0 - Avaliação do eixo ATP-adenosina em linfócitos na infecção por SARS-CoV-2
• Beneficiário: Maria Notomi Sato
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 19/02679-7 - Efeito da suplementação com antioxidante materna e paterna em processo inflamatório pulmonar da prole de camundongos
• Beneficiário: Ricardo Wesley Alberca Custódio
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 19/25119-7 - Interface materno-fetal: imunopatogênese e intervenção vacinal em infecções virais
• Beneficiário: Maria Notomi Sato
• Modalidade de apoio: Auxílio à Pesquisa - Temático