An unexpected isomerisation of Isoquinuclidines

Autor(es)

Moura, Rebeca G. G. ; Batista, Patrick R. R. ; Ducati, Lucas C. C. ; Yamaguchi, Lydia F. F. ; Marzorati, Liliana

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF PHYSICAL ORGANIC CHEMISTRY; v. N/A, p. 8-pg., 2023-05-31.

Resumo

The Diels-Alder reaction of three chiral dihydro-2H-[2,3-a]oxazolopyridines with N-methylmaleimide afforded the corresponding chiral cycloadducts as diastereomeric mixtures. In the presence of a solvent, some of the originally formed adducts underwent isomerisation to new isoquinuclidines. (AU)

• Processo FAPESP: 18/07308-4 - Efeito do solvente em cálculos de tensor blindagem e constante de acoplamento de complexos dinucleares de platina (III) via dinâmica molecular ab initio
• Beneficiário: Patrick Rodrigues Batista
• Modalidade de apoio: Bolsas no Brasil - Doutorado