Busca avançada
Ano de início
Entree


Kinetic Profile of Urine Metabolites after Acute Intake of a Phenolic Compounds-Rich Juice of Jucara (Euterpe edulis Mart.) and Antioxidant Capacity in Serum and Erythrocytes: A Human Study

Texto completo
Autor(es):
Mostrar menos -
Cardoso, Alyne Lizane ; Teixeira, Luciane de Lira ; Hassimotto, Neuza Mariko Aymoto ; Baptista, Sheyla de Liz ; Copetti, Candice Lais Knoner ; Rieger, Debora Kurrler ; Vieira, Francilene Gracieli Kunradi ; Micke, Gustavo Amadeu ; Vitali, Luciano ; de Assis, Maria Alice Altenburg ; Schulz, Mayara ; Fett, Roseane ; da Silva, Edson Luiz ; Di Pietro, Patricia Faria
Número total de Autores: 14
Tipo de documento: Artigo Científico
Fonte: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; v. 24, n. 11, p. 15-pg., 2023-05-31.
Resumo

The jucara palm tree produces a small spherical and black-purple fruit similar to acai. It is rich in phenolic compounds, especially anthocyanins. A clinical trial evaluated the absorption and excretion of the main bioactive compounds in urine and the antioxidant capacity in serum and erythrocytes of 10 healthy subjects after jucara juice intake. Blood samples were collected before (0.0 h) and 0.5 h, 1 h, 2 h, and 4 h after a single dose (400 mL) of jucara juice, while urine was collected at baseline and 0-3 and 3-6 h after juice intake. Seven phenolic acids and conjugated phenolic acids were identified in urine deriving from the degradation of anthocyanins: protocatechuic acid, vanillic acid, vanillic acid glucuronide, hippuric acid, hydroxybenzoic acid, hydroxyphenylacetic acid, and ferulic acid derivative. In addition, kaempferol glucuronide was also found in urine as a metabolite of the parent compound in jucara juice. Jucara juice caused a decrease in the total oxidant status of serum after 0.5 h in comparison to baseline values (p < 0.05) and increased the phenolic acid metabolites excretion. This study shows the relationship between the production of metabolites of jucara juice and the total antioxidant status in human serum, indicating evidence of its antioxidant capacity. (AU)

Processo FAPESP: 13/07914-8 - FoRC - Centro de Pesquisa em Alimentos
Beneficiário:Bernadette Dora Gombossy de Melo Franco
Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs