A Single Bout of High Heels Dancing Causes an Increase in Circulating Markers of Muscle Tissue Degradation and MMP-3 in Young Healthy Women

Autor(es)

Silva, Jamila ; Borges, Leandro ; Weimann, Eleine ; Dias, Beatriz Belmiro ; Faria, Flavio Gomes ; Salgado, Beatriz Ferreira ; de Freitas, Paulo ; Pithon-Curi, Tania Cristina ; Hatanaka, Elaine

• Tipo de documento: Artigo Científico
• Fonte: TRANSLATIONAL SPORTS MEDICINE; v. 2023, p. 7-pg., 2023-06-01.

Resumo

Prolonged wearing of high heels can cause chronic injury and inflammation. Herein, we investigated the presence of muscle injury, inflammation, and neutrophil function in young women after a single bout of stiletto dance class. Sixteen volunteers (23.4 +/- 3.8 years; 61.7 +/- 8.1 kg; 23.4 +/- 2.3 kg/m(2); and 27.2 +/- 3.8% body fat) participated in the study. The plasma biomarkers matrix metalloproteinase 3 (MMP-3), muscle damage (myoglobin (Mb), total creatine kinase (CK), and lactate dehydrogenase (LDH)), and inflammation (interleukin 8 (IL-8), tumour necrosis factor-alpha (TNF-alpha), interleukin (IL]-1 beta, and IL-6) were quantified before and immediately after a single stiletto class (60 min) of moderate intensity. After class, our data showed that the plasma concentration of MMP-3, Mb, and CK increased by 56% (p = 0.04; d = 0.8), 113% (p = 0.007; d = 1.1), and 21% (p < 0.001; d = 0.4), respectively. Reactive oxygen species produced by neutrophils and the plasma concentration of IL-8, TNF-alpha, IL-1 beta, and IL-6 were not affected under the study conditions. We concluded that a single bout of stiletto dance class caused muscle damage but did not alter the plasma concentration of proinflammatory cytokines. These findings are crucial in preventing the progress of chronic injuries that are often noted in dancers with synovitis and arthritis. (AU)

• Processo FAPESP: 11/21441-0 - Instalação e resolução do processo inflamatório em bailarinas clássicas: estudo das alterações sistêmicas e leucocitárias
• Beneficiário: Elaine Hatanaka Dermargos
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 20/12267-5 - Ativação linfocitária após uma aula de alta intensidade de dança de rua.
• Beneficiário: Elaine Hatanaka Dermargos
• Modalidade de apoio: Auxílio à Pesquisa - Publicações científicas - Artigo
• Processo FAPESP: 14/21185-1 - Efeito do treinamento físico moderado sobre o estado inflamatório e as funções leucocitárias de indivíduos diabéticos
• Beneficiário: Elaine Hatanaka Dermargos
• Modalidade de apoio: Auxílio à Pesquisa - Regular