| Texto completo | |
| Autor(es): |
Kouyoumdjian, Joao Aris
;
Graca, Carla Renata
Número total de Autores: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | FRONTIERS IN NEUROLOGY; v. 14, p. 10-pg., 2023-02-23. |
| Resumo | |
The aim of this study was to measure the muscle fiber conduction velocity (MFCV) in situ in the tibialis anterior muscle in healthy subjects. A total of 36 subjects matched for age and sex were studied. The MFCV was measured with a concentric needle by intramuscular monopolar needle electrical activation at a distance of 50 mm. The mean consecutive difference (MCD) of <5 mu s was obtained after a median of 62 muscle fiber action potentials (MFAPs), confirming a direct muscle fiber activation. The measuring latency was at the median point of ascending depolarizing line of the MFAP. The calculated MFCV from 784 MFAPs was 4.10 +/- 0.66 m/s, 3.99 +/- 0.57 for female subjects (95%, 2.85 to 5.13), and 4.20 +/- 0.73 for male subjects (95%, 2.74 to 5.67). The MFCV was 5.22% faster in male subjects. The calculated fast-to-slow MFCV ratio (F/S ratio) was 1.47 for female subjects (95%, 1.27 to 2.54) and 1.67 for male subjects (95%, 1.31 to 3.74). Aging significantly increased the F/S ratio. As the MFCVs mainly depend on the muscle diameter, their assessment is a quick and helpful tool for estimating it. Its variability by the F/S ratio is also a powerful tool in the follow-up of some neuromuscular disorders. (AU) | |
| Processo FAPESP: | 22/02291-1 - Avaliação eletrofisiológica do jitter e da velocidade de condução das fibras musculares in situ após COVID-19 |
| Beneficiário: | João Aris Kouyoumdjian |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |