TiO2 nanotube-containing glass ionomer cements display reduced aluminum release rates

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da Silva Morais, Ana Mara ; Reali Pereira, Ysadora Mayara ; de Souza-Araujo, Isaac Jordao ; Silva, Daniel Furtado ; Arias Pecorari, Vanessa Gallego ; Gomes, Orisson Ponce ; Nociti-Junior, Francisco Humberto ; Puppin-Rontani, Regina Maria ; Vieira-Junior, Waldemir Francisco ; Lisboa-Filho, Paulo Noronha ; Kantovitz, Kamila Rosamilia

• Tipo de documento: Artigo Científico
• Fonte: BRAZILIAN ORAL RESEARCH; v. 36, p. 8-pg., 2022-01-01.

Resumo

Titanium dioxide nanotubes (TiO2-nts) were incorporated into a glass ionomer cement (GIC) with improved mechanical properties and antibacterial activity. The aims of the present in vitro study were to define the elemental characterization, aluminum (Al) release rate, and initial working time for GIC reinforced with TiO2-nts, in an experimental caries model. TiO2-nts were incorporated into GIC powder components at 5% by weight, and compared with unblended GIC. Experimental approaches used energy-dispersive spectrometry (EDS), atomic absorption spectrophotometry (AAS), and brightness loss to define surface element properties, Al release rates, and initial working time, respectively. Statistical analysis was performed by 2-way ANOVA, Tukey's test, generalized linear models, and Student's t test (a = 0.05). EDS data analysis revealed that TiO2-nts incorporated into GIC had no significant impact on the typical elemental composition of GICs in an in vitro caries model. Regarding the demineralizing solution, GIC with TiO2-nt significantly decreased the Al release rate, compared with the control group (p < 0.0001). Moreover, TiO2-nt incorporated into GIC did not alter the initial working time of the material (p > 0.05). These findings add information to our scientific body of knowledge concerning the potential impact of TiO2-nt on the performance of conventional GICs. (AU)

• Processo FAPESP: 16/13786-0 - Influência de Nova Nanotecnologia nas Propriedades Físico-Químicas-Biológicas do Cimento de Ionômero de Vidro Convencional
• Beneficiário: Kamila Rosamilia Kantovitz
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 19/14078-8 - Avaliação do efeito da incorporação de nanotubos de dióxido de titânio ao cimento de ionômero de vidro convencional sobre suas propriedades biológicas
• Beneficiário: Kamila Rosamilia Kantovitz
• Modalidade de apoio: Auxílio à Pesquisa - Regular