Fish Oil Supplementation Improves the Repeated-Bout Effect and Redox Balance in 20-30-Year-Old Men Submitted to Strength Training

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Barquilha, Gustavo ; Dos Santos, Cesar Miguel Momesso ; Cacula, Kim Guimaraes ; Santos, Vinicius Coneglian ; Polotow, Tatiana Geraldo ; Vasconcellos, Cristina Vardaris ; Gomes-Santos, Jose Alberto Fernandes ; Rodrigues, Luiz Eduardo ; Lambertucci, Rafael Herling ; Serdan, Tamires Duarte Afonso ; Levada-Pires, Adriana Cristina ; Hatanaka, Elaine ; Cury-Boaventura, Maria Fernanda ; de Freitas, Paulo Barbosa ; Pithon-Curi, Tania Cristina ; Masi, Laureane Nunes ; Barros, Marcelo Paes ; Curi, Rui ; Gorjao, Renata ; Hirabara, Sandro Massao

• Tipo de documento: Artigo Científico
• Fonte: NUTRIENTS; v. 15, n. 7, p. 19-pg., 2023-04-01.

Resumo

Herein, we investigated the effect of fish oil supplementation combined with a strength-training protocol, for 6 weeks, on muscle damage induced by a single bout of strength exercise in untrained young men. Sixteen men were divided into two groups, supplemented or not with fish oil, and they were evaluated at the pre-training period and post-training period. We investigated changes before and 0, 24, and 48 h after a single hypertrophic exercise session. Creatine kinase (CK) and lactate dehydrogenase (LDH) activities, plasma interleukin-6 (IL-6) and C-reactive protein (CRP) levels, and the redox imbalance were increased in response to the single-bout session of hypertrophic exercises at baseline (pre-training period) and decreased during the post-training period in the control group due to the repeated-bout effect (RBE). The fish oil supplementation exacerbated this reduction and improved the redox state. In summary, our findings demonstrate that, in untrained young men submitted to a strength-training protocol, fish oil supplementation is ideal for alleviating the muscle injury, inflammation, and redox imbalance induced by a single session of intense strength exercises, highlighting this supplementation as a beneficial strategy for young men that intend to engage in strength-training programs. (AU)

• Processo FAPESP: 18/09868-7 - Mecanismos celulares e moleculares envolvidos na resistência à insulina e inflamação em ratos Wistar obesos e Goto-Kakizaki magros: causas e associações com dieta e exercício físico
• Beneficiário: Rui Curi
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 10/08147-2 - Efeito do treinamento de força sobre parâmetros morfofuncionais, hormonais, inflamatórios e de lesão em homens e mulheres suplementados ou não com ácidos graxos ômega-3
• Beneficiário: Sandro Massao Hirabara
• Modalidade de apoio: Auxílio à Pesquisa - Regular