| Texto completo | |
| Autor(es): |
Bedani, Raquel
;
Rossi, Elizeu Antonio
;
Umbelino Cavallini, Daniela Cardoso
;
Pinto, Roseli Aparecida
;
Vendramini, Regina Celia
;
Augusto, Elaine Moura
;
Parra Abdalla, Dulcineia Saes
;
Isay Saad, Susana Marta
Número total de Autores: 8
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Food Research International; v. 73, p. 7-pg., 2015-07-01. |
| Resumo | |
This study aimed to investigate the effect of a synbiotic fermented soy product supplemented with okara (a by-product from soybean) on cardiovascular disease risk markers in healthy men. In a randomized, double-blinded, placebo controlled trial, thirty-six normocholesterolemic men were assigned to two groups. Subjects consumed daily 100 g of soy-based product fermented with Lactobacillus acidophilus La-5, Bifidobacterium animalis subsp. lactis Bb-12, and Streptococcus thermophilus (starter culture) (synbiotic group - S) (n = 18) or 100 g of unfermented soy-based product (placebo group - P) (n = 18) for 8 weeks. Fasting blood samples and anthropometric measurements were collected at the baseline (To), the end of week 4 (T-4), and the end of week 8 (T-8). Serum lipids, C-reactive protein, fibrinogen, and electronegative LDL were also analysed on To, T-4, and T-8. During the period of daily soy-based product consumption (from To to T-8) the LDL-C mean decreased significantly (p < 0.05) in groups, resulting in a significant (p < 0.05) improvement of the LDL-C/HDL-C ratio. Comparing mean differences (T-8-T-0) between the two groups, the trend of LDL-C and LDL-C/HDL-C ratio reductions was higher in group S (14.1 mg/dL and 038 mg/dL, respectively) than group P (4.9 mg/dL and 0.17 mg/dL, respectively) (p > 0.05). Our results suggest limited lipid-lowering effects of synbiotic soy-based product supplemented with okara on cardiovascular risk markers in normocholesterolemic men. (C) 2014 Elsevier Ltd. All rights reserved. (AU) | |
| Processo FAPESP: | 09/51169-0 - Desenvolvimento de um iogurte de soja probiótico enriquecido com cálcio e suplementado com inulina e farinha de okara: resistência dos probióticos in vitro e influência sobre os marcadores laboratoriais de risco para aterosclerose em humanos |
| Beneficiário: | Susana Marta Isay Saad |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 09/51168-3 - Desenvolvimento de um iogurte de soja probiótico enriquecido com cálcio e suplementado com inulina e farinha de okara: resistência dos probióticos in vitro e influência sobre os marcadores laboratoriais de risco para aterosclerose em humanos |
| Beneficiário: | Raquel Bedani Salvio |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |