Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Autor(es)

Lima, Cassio A. ; Correa, Luciana ; Byrne, Hugh J. ; Zezell, Denise M. ; Brown, JC ; VanLeeuwen, TG

• Tipo de documento: Artigo Científico
• Fonte: CLINICAL AND PRECLINICAL OPTICAL DIAGNOSTICS II; v. 11073, p. 3-pg., 2019-01-01.

Resumo

Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin. (AU)

• Processo FAPESP: 05/51689-2 - Centro de Pesquisa em Óptica e Fotônica - UNICAMP (CEPOF-UNICAMP)
• Beneficiário: Hugo Luis Fragnito
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs